UCLA Center for AIDS Research (CFAR)

加州大学洛杉矶分校艾滋病研究中心 (CFAR)

• 批准号: 8072329
• 负责人: Jerome A. Zack
• 金额: $ 12.6万
• 依托单位: UNIVERSITY OF CALIFORNIA LOS ANGELES
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-06-01 至 2012-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8072329
• 关键词: UCLA; Center; AIDS; Research; CFAR

This application constitutes a renewal on the part of the University of California/Los Angeles (UCLA) for a Center for AIDS Research (CFAR) grant. This grant will fund activities and programs conducted by the UCLA CFAR within the UCLA AIDS Institute. The UCLA CFAR was set up in 1988, and the AIDS Institute was established in 1992 to coordinate all AIDS research, clinical and educational activities at the University and its seven affiliated teaching hospitals under one central administration. The overall organization of the AIDS Institute and the CFAR was restructured in 2005, in order to more efficiently and effectively manage a faculty that has grown by 30% in the last five years and CFAR-applicable grants that have risen by 50% since we submitted our last renewal application. This renewal application includes CFAR core services and activities that are designed to advance knowledge of HIV/AIDS through the basic, clinical, and behavioral sciences. The overall mission of the UCLA CFAR is to create synergies among diverse disciplines that result in significant breakthroughs in the understanding, prevention and treatment of HIV infection¿with particular emphasis on high-value cross-disciplinary collaborations. The UCLA CFAR consists of more than 200 faculty investigators who are responsible for more than 250 research projects that encompass virtually all aspects of HIV/AIDS biology, clinical studies, and behavioral science. UCLA has consistently been ranked among the top institutions for excellence in AIDS research, education and teaching, and clinical programs. Metropolitan Los Angeles is a major epicenter for the AIDS epidemic and one of the most culturally diverse regions in the nation, and our programs are designed to reach out to these diverse communities. We are particularly proud that 50% of the patients recruited into our clinical trials in recent years are members of minority communities. The role of the CFAR is to foster collaboration and build linkages both within and outside the university, through support of scientific and administrative core facilities, and the provision of seed grant funding for highly meritorious collaborative research projects. The action plan for the first year of requested support, January 2008 to December 2008, is summarized as follows: The CFAR plans to continue supporting eight of the cores funded by the previous CFAR grant: Administrative Core, Developmental Core, Virology/BSL3 Tissue Culture Core, Cytometry Core, Mouse/Human Chimera Core, Gene and Cellular Therapy Core, Mucosal Immunology Core, and the Biostatistics Core. Based upon changing epidemiology, needs assessments, strategic planning and revised short- and long-term goals, two cores were eliminated and a Clinical Research Facilitation Core and a Consultation Core are added.

该申请构成了加利福尼亚大学/洛杉矶分校（UCLA）的续约 艾滋病研究中心（CFAR）赠款。该赠款将资助由 加州大学洛杉矶分校艾滋病研究所内的UCLA CFAR。 UCLA CFAR成立于1988年，艾滋病研究所 成立于1992年，以协调大学的所有艾滋病研究，临床和教育活动 以及在一家中央政府领导下的七家会员教学医院。总体组织 艾滋病研究所和CFAR于2005年恢复，以更有效地管理 在过去五年中增长了30％，CFAR可申请的赠款增长了30％，增加了50％ 由于我们提交了最后一次续签申请。此续订应用程序包括CFAR Core Services和 旨在通过基本，临床和行为提高艾滋病毒/艾滋病知识的活动 科学。 UCLA CFAR的总体使命是在潜水学科中建立协同作用，从而导致 在理解，预防和治疗艾滋病毒感染方面的重大突破中 强调高价值跨学科合作。 UCLA CFAR由200多名教师组成 负责250多个研究项目的调查人员，这些项目几乎包括 艾滋病毒/艾滋病生物学，临床研究和行为科学。加州大学洛杉矶分校一直在 艾滋病研究，教育和教学以及临床计划的卓越卓越机构。大都市 洛杉矶是艾滋病流行病的主要中心，也是最多样化的地区之一 国家和我们的计划旨在与这些潜水员社区接触。我们特别自豪 近年来，有50％的患者进入我们的临床试验是少数民族社区的成员。 CFAR的作用是促进大学内外的协作和建立联系， 通过支持科学和行政核心设施，以及为种子赠款提供资金 高度有功的协作研究项目。 2008年1月至2008年12月，要求支持第一年的行动计划总结为 如下：CFAR计划继续支持上一家CFAR资助资助的八个核心： 行政核心，发育核心，病毒学/BSL3组织培养核心，细胞术核心， 小鼠/人类嵌合内核，基因和细胞疗法核心，粘膜免疫学核心以及 生物统计学核心。基于变化的流行病学，需求评估，战略计划和修订 短期和长期目标，消除了两个核心，临床研究促进核心和一个 添加了咨询核心。