Pathlogy Shared Resource

病理学共享资源

基本信息

批准号：
8369398
负责人：
MICHELE CARBONE
金额：
$ 4.83万
依托单位：
UNIVERSITY OF HAWAII AT MANOA
依托单位国家：
美国
项目类别：
财政年份：
2012
资助国家：
美国
起止时间：
2012-07-01 至 2017-06-30
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/8369398
关键词：
Advisory Committees Area Atlases Basic Science Biocompatible Materials Biological Assay Biological Markers Blood specimen Breast Caliber Cancer Center Cancer Center Support Grant Cancer Etiology Certification Clinical Clinical Research Collection Colorectal Colorectal Cancer Committee Members Confidentiality of Patient Information Consent Consultations Country County Custom Data Data Element Databases Decision Making Development Documentation Endometrium Epidemiologic Studies Excision Female Genital Neoplasms Freezing Fresh Tissue Funding Future Government Hawaii Health Insurance Portability and Accountability Act Hematoxylin and Eosin Staining Method Histology Histopathology Hospitals Human Human Subject Research Image Immunohistochemistry In Situ Hybridization Individual Institution Institutional Review Boards International Iowa Laboratories Laws Link Liver Los Angeles Malignant Neoplasms Malignant neoplasm of liver Malignant neoplasm of ovary Medical Medical center Methods Microscopic Microscopy Names Operative Surgical Procedures Ovary Pancreas Paraffin Paraffin Embedding Parents Pathologic Pathologist Pathology Patients Performance Periodic acid Schiff stain method Population Precancerous Conditions Preparation Process Protocols documentation Provider Qualifying Race Reagent Recording of previous events Reporting Research Research Activity Research Personnel Research Project Grants Research Proposals Resource Sharing Resources Retrieval SEER Program Sampling Savings Services Silver Site Slide Specific qualifier value Specimen Stage at Diagnosis Staining method Stains System Testing Time Tissue Banking Tissue Banks Tissue Microarray Tissue Procurements Tissues Translational Research Transplantation Trichrome stain method Tumor Tissue Universities Work age group authority base biobank cancer care cancer genome case-by-case basis computerized cost experience falls human subject laser capture microdissection malignant breast neoplasm material transfer agreement meetings member population based prevent prognostic programs prospective protocol development repository research study sample collection sample fixation technology development tissue resource tool tumor

项目摘要

The Pathology Shared Resource (PSR) was created approximately 7 years ago to provide histology and tissue procurement services to support basic, epidemiologic, translational, and clinical research studies conducted both within and outside of the University of Hawai'i Cancer Center (UHCC). Prior to the existence of the PSR, tissue based research at the UHCC was severely limited due to lack of a centralized histopathology service and tissue repository. Since its establishment, usage of the PSR has consistently increased and has facilitated multiple high quality research endeavors by UHCC members. Current services offered by the Resource include a full range of histology services, professional pathology consultation, as well as specialized laboratory services such as tissue microarray (TMA) construction and consultation for laser-capture microdissection (LCM). In addition to these functions, the PSR manages a large, clinically annotated archival tissue repository and facilitates investigator-initiated fresh tissue collection from area hospitals. Future directions for the PSR include establishment of a prospectively collected biorepository in partnership with Queens Medical Center (QMC), the largest cancer care provider in Hawai'i, as well as other consortium hospital members. As a newly emerging facility, the PSR was not supported by the CCSG during the prior funding period. Given that the PSR is now a mature enterprise whose endeavors are expected to continue to expand, we now request CCSG support. CCSG support will also be crucial to the future functioning of this resource, in view of the recent termination of SEER funding for the archival tissue repository in 2010.

大约7年前创建了病理共享资源（PSR），以提供组织学和组织采购服务，以支持夏威夷大学癌症中心（UHCC）内外进行的基本，流行病学，转化和临床研究。在存在PSR之前，由于缺乏集中的组织病理学服务和组织存储库，在UHCC的基于组织的研究受到严重限制。自成立以来，PSR的使用一直在不断增加，并促进了UHCC成员的多项高质量研究努力。资源提供的当前服务包括全方位的组织学服务，专业病理学咨询以及专业实验室服务，例如组织微阵列（TMA）的激光捕获微解析（LCM）咨询。除这些功能外，PSR还管理着一个大型的临床注释的档案库存储库，并促进了研究人员从地区医院发起的新鲜组织收集。 PSR的未来指示包括与夏威夷最大的癌症护理提供商以及其他财团成员的皇后医学中心（QMC）合作建立了前瞻性收集的生物座席。作为新兴的设施，在先前的资金期间，CCSG不支持PSR。鉴于PSR现在是一家成熟的企业，其努力有望继续扩展，我们现在请求CCSG支持。鉴于2010年最近终止了对档案组织存储库的SEER资金，CCSG支持也将对该资源的未来运作至关重要。