Cincinnati Regional Coordinating Stroke Center (Cincinnati RCC)

辛辛那提地区卒中协调中心（辛辛那提 RCC）

• 批准号: 8662833
• 负责人: DAWN O KLEINDORFER
• 金额: $ 39.63万
• 依托单位: UNIVERSITY OF CINCINNATI
• 依托单位国家: 美国
• 财政年份: 2013
• 资助国家: 美国
• 起止时间: 2013-09-30 至 2018-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8662833
• 关键词: Acute; Address; Adult; Agreement; Back; Budgets; Caring; Cause of Death; Childhood; Clinical; Clinical Trials; Clinical Trials Design; Clinical Trials Network; Communication; Community Outreach; Education; Electronics; Emergency Situation; Faculty; Foundations; Funding; Goals; Hospitals; Individual; Institution; Institutional Review Boards; International; Ischemic Stroke; Lead; Leadership; Metric; Modeling; National Institute of Neurological Disorders and Stroke; Neurology; Observational Study; Outpatients; Participant; Patients; Persons; Phase; Phase I Clinical Trials; Physicians; Population Heterogeneity; Prevention; Principal Investigator; Race; Recovery; Recruitment Activity; Rehabilitation therapy; Research; Research Infrastructure; Scientist; Site; Stroke; Stroke prevention; Testing; Training; United States National Institutes of Health; Universities; Wages; Work; acute stroke; career; data management; data quality; design; disability; ethnic minority population; experience; improved; innovation; multidisciplinary; neurosurgery; next generation; patient population; pilot trial; programs; public health priorities; public health relevance; skills; socioeconomics; stroke therapy; success; theories; working group

DESCRIPTION (provided by applicant): The objectives of the proposed NINDS Stroke Clinical Trials Network (NSTN) are to harness multidisciplinary stroke expertise to collaboratively and efficiently design and execute stroke clinical trials in all phases. We will bring a fully integratd clinical trial network approach to stroke more broadly and cohesively as a Regional Coordinating Center (RCC) of the NSTN. Our goals are to (1) efficiently implement trials, recruit and retain participants, and optimize data quality as an RCC, (2) actively participate in the NSTN as experienced scientists, clinicians, trialists, and coordinators, and (3) successfully train the next generation of stroke clinical trialists. We will achieve these goals by bringing experienced leadership, access to a diverse patient population, an established research infrastructure, and a supportive administration. Our institution has shown their commitment to the NSTN by agreeing to use a standardized Master Trial Agreement, employ a centralized IRB review, and provide additional institutional funds to support the RCC trainee. We propose to be a key partner in the NSTN working to bring the most clinically impactful stroke therapies to our patients through high-quality stroke trials.

描述（由申请人提供）：拟议的NINDS中风临床试验网络（NSTN）的目标是利用多学科的中风专业知识，以在所有阶段进行协作，有效地设计和执行中风临床试验。我们将带来一种完全集成的临床试验网络方法，以更广泛和凝聚力作为NSTN的区域协调中心（RCC）。我们的目标是（1）有效实施试验，招募和保留参与者，并优化数据质量作为RCC，（2）积极参与NSTN，作为经验丰富的科学家，临床医生，试验员和协调员，以及（3）成功培训 下一代中风临床试验者。我们将通过带来经验丰富的领导力，进入多样化的患者人群，已建立的研究基础设施以及支持性管理来实现这些目标。我们的机构通过同意使用标准化的总审判协议，采用集中的IRB审查，并提供额外的机构资金来支持RCC培训生，从而表明了他们对NSTN的承诺。我们建议成为NSTN的关键合作伙伴，致力于通过高质量的中风试验为患者带来最大临床影响的中风疗法。