Evaluation of Protective Clothing to Prevent Diisocyanate Exposures in the Collis

预防科利斯二异氰酸酯暴露的防护服的评估

• 批准号: 8088180
• 负责人: MICHAEL G YOST
• 金额: $ 36.17万
• 依托单位: UNIVERSITY OF WASHINGTON
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-09-01 至 2013-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8088180
• 关键词: Evaluation; Protective; Clothing; Prevent; Diisocyanate

DESCRIPTION (provided by applicant): The collision repair industry in the Puget Sound is composed of numerous small businesses with ineffective health and safety practices. Paint spraying and mixing painting process, besides being an inhalation hazard, contribute largely to a painter's dermal exposure. Isocyanates are present in high concentration in the final "clear" coat. Isocyanates are known irritants, sensitizers, and a leading cause of work-related asthma in Washington State. Painters use respirators, but not necessarily gloves and coveralls to protect their skin. Little information currently is available on the effectiveness of protective clothing for spray painters because no systematic investigation for use with isocyanates has ever been conducted. The currently available information is largely focused on comfort, elasticity, lint-free qualities, or solvent resistance, rather than resistance to isocyanates. Manufacturer and supplier compatibility charts regarding protection from isocyanates is limited and conflicting. This is not surprising since isocyanates have chemical characteristics that make testing difficult with standard methods used for protective clothing. We are proposing a novel and systematic laboratory and workplace assessment of the efficacy of gloves and coveralls for protection against isocyanates. We recognize there are many variables affecting a worker's effective use of protective equipment. Therefore, we will also facilitate focus groups with painters to share our findings and assess strategies to implement future interventions. We will also develop an improved analytical method for detecting the complex mixtures of polyisocyanates in clear coats. Public Health Relevance: Isocyanates used in the auto-collision repair industry are recognized as an occupational asthma and these workers are at high risk for work-related asthma. protective clothing used in this industry lacks basic data on efficacy. This study will evaluate the effectiveness of protective clothing, such as gloves preventing isocyanate exposures among auto-collision repair workers. We will also develop an improved analytical method for detecting the complex mixtures of polyisocyanates in clear coats.

描述（由申请人提供）： 普吉特湾的碰撞维修行业由众多健康和安全实践无效的小企业组成。油漆喷涂和混合涂装过程除了存在吸入危险外，还很大程度上导致油漆工的皮肤暴露。异氰酸酯在最终的“透明”涂层中以高浓度存在。异氰酸酯是已知的刺激物、致敏剂，也是华盛顿州工作相关哮喘的主要原因。画家使用呼吸器，但不一定使用手套和工作服来保护皮肤。目前关于喷漆工防护服有效性的信息很少，因为尚未对异氰酸酯的使用进行系统研究。目前可获得的信息主要集中在舒适性、弹性、不起毛质量或耐溶剂性，而不是耐异氰酸酯性。制造商和供应商有关异氰酸酯防护的兼容性图表有限且相互矛盾。这并不奇怪，因为异氰酸酯的化学特性使得防护服标准方法的测试变得困难。我们提议对手套和工作服的异氰酸酯防护功效进行新颖且系统的实验室和工作场所评估。我们认识到有许多变量会影响工人有效使用防护装备。因此，我们还将促进与画家的焦点小组分享我们的发现并评估实施未来干预措施的策略。我们还将开发一种改进的分析方法，用于检测透明涂层中多异氰酸酯的复杂混合物。 公共健康相关性：汽车碰撞维修行业使用的异氰酸酯被认为是一种职业性哮喘，这些工人患工作相关哮喘的风险很高。该行业使用的防护服缺乏功效基础数据。这项研究将评估防护服的有效性，例如防止汽车碰撞维修工人接触异氰酸酯的手套。我们还将开发一种改进的分析方法，用于检测透明涂层中多异氰酸酯的复杂混合物。

项目成果

Residual Isocyanates in Medical Devices and Products: A Qualitative and Quantitative Assessment.

医疗器械和产品中的残留异氰酸酯：定性和定量评估。

• 发表时间: 2016
• 影响因子: 2.7
• 作者: Franklin, Gillian;Harari, Homero;Ahsan, Samavi;Bello, Dhimiter;Sterling, David A;Nedrelow, Jonathan;Raynaud, Scott;Biswas, Swati;Liu, Youcheng
• 通讯作者: Liu, Youcheng

Development of a permeation panel to test dermal protective clothing against sprayed coatings.

开发渗透小组来测试真皮防护服对喷涂涂层的抵抗力。

• 发表时间: 2011-03
• 作者: Ceballos, Diana M;Yost, Michael G;Whittaker, Stephen G;Reeb;Camp, Janice;Dills, Russell
• 通讯作者: Dills, Russell

Protection efficacy of gloves against components of the solvent in a sprayed isocyanate coating utilizing a reciprocating permeation panel.

利用往复式渗透板对喷涂异氰酸酯涂层中的溶剂成分进行手套防护的效果。

• 发表时间: 2015-04
• 作者: Ceballos, Diana M;Reeb;Sasakura, Miyoko;Dills, Russell;Yost, Michael G
• 通讯作者: Yost, Michael G

Understanding factors that influence protective glove use among automotive spray painters.

了解影响汽车喷漆工使用防护手套的因素。

• 发表时间: 2014
• 影响因子: 2
• 作者: Ceballos, Diana;Reeb;Glazer, Patricia;Murphy;Yost, Michael
• 通讯作者: Yost, Michael

Testing of glove efficacy against sprayed isocyanate coatings utilizing a reciprocating permeation panel.

使用往复式渗透板测试手套对喷涂异氰酸酯涂层的功效。

• 发表时间: 2014-01
• 作者: Ceballos, Diana M;Sasakura, Miyoko;Reeb;Broadwater, Kendra;Milbauer, Mark;Crampton, Robert;Dills, Russell;Yost, Michael G
• 通讯作者: Yost, Michael G