Clinical Services Core

临床服务核心

• 批准号: 8375601
• 负责人: BENIGNO RODRIGUEZ
• 金额: $ 18.56万
• 依托单位: CASE WESTERN RESERVE UNIVERSITY
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/8375601
• 关键词: Acquired Immunodeficiency Syndrome; American; Area; Biometry; Clinical; Clinical Management; Clinical Services; Clinical Trials; Collaborations; Data; Data Set; Databases; Development; Epidemiology; Faculty; HIV; HIV vaccine; Human Subject Research; Institution; Laboratories; Link; Mining; Patient Care; Patients; Play; Process; Quality Control; Research; Research Activity; Research Design; Research Personnel; Research Project Grants; Research Support; Resources; Role; Sampling; Services; Specimen; Study Subject; Support System; System; Training; cohort; data structure; design; interest; member; microbicide; repository; research study; tool; vaccine development; volunteer

The Clinical Services Core (CSC) is a central resource designed to support each step in the development, conduct, and analysis of all human subject research projects originated from or supported by the Case CFAR. Specific aims of the CSC include: ¿ Maintain and expand a comprehensive and accessible Patient Care and Research Database (PCRD). ¿ Maintain and expand a specimen repository linked to the patient care database. ¿ Provide researchers with access to patients pre-selected for interest and identified as eligible (through mining of the Patient Care and Research Database) to participate in HIV clinical trials or other research studies. ¿ Maintain, expand, and provide access to a newly established database of over 800 HIV-negative volunteers in the Cleveland area who are interested in participating in HIV research. ¿ Coordinate the exchange of clinical and laboratory data with other institutions participating in collaborative projects designed to conduct research on HIV observational data. The Case CFAR is a founding member of two such collaborations, the CFAR Network of Integrated Clinical Systems (CNICS) and the North American AIDS Cohort Collaboration on Research and Design (NAACCORD). ¿ Assist CFAR researchers in planning and designing studies that use the PCRD and the specimen repository by helping investigators formulate research questions that take full advantage of the data and specimens available through the Core. ¿ Provide biostatistical and epidemiologic support and advice to Case CFAR investigators, and provide training and faculty development in epidemiology and biostatistics.

临床服务核心（CSC）是一种中央资源，旨在支持所有人类主题研究项目的开发，进行和分析的每个步骤，该项目源自案件CFAR或支持。 CSC的具体目标包括： »维护和扩展一个全面且可访问的患者护理和研究数据库（PCRD）。 »维护和扩展与患者护理数据库相关的标本存储库。 �为研究人员提供与预先选择的兴趣的患者，并确定为合格（通过挖掘患者护理和研究数据库），以参与HIV临床试验或其他研究。 »在克利夫兰地区有800多名HIV阴性志愿者的新成立数据库，并提供对参加HIV研究感兴趣的新数据库。 »协调临床和实验室数据与参与旨在进行HIV观察数据研究的协作项目的其他机构的交换。 CASE CFAR是两个这样的合作的创始成员，即集成临床系统（CNIC）和北美艾滋病研究与设计协作（NAACCORD）的CFAR网络。 �通过帮助调查人员提出研究问题，以充分利用通过核心可用的数据和标本来帮助调查人员提出研究问题，以协助CFAR研究人员计划和设计使用PCRD和标本存储库。 �为案例CFAR调查人员提供生物统计学和流行病学的支持和建议，并提供流行病学和生物统计学方面的培训和教师发展。