SOFTWARE FOR AUDITORY PROSTHESIS RESEARCH

用于听觉修复研究的软件

• 批准号: 7803499
• 负责人: RAYMOND L GOLDSWORTHY
• 金额: $ 9.59万
• 依托单位: SENSIMETRICS CORPORATION
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-05-24 至 2011-05-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7803499
• 关键词: Auditory; Bilateral; Bionics; Boston; Brain Stem; Cell Nucleus; Clinical; Cochlear Implants; Collaborations; Computer software; Custom; Development; Development Plans; Devices; Diagnostic; Electric Stimulation; Evaluation; Experimental Designs; Freedom; Funding; Imagery; Implant; Measurement; Measures; Midbrain structure; Minnesota; Pediatric Hospitals; Phase; Procedures; Process; Psychophysics; Psychophysiology; Request for Applications; Research; Research Support; Resources; Software Design; Speech; Structure; System; Texas; Training; Translating; Universities; Work; clinically relevant; computerized data processing; design; flexibility; improved; meetings; novel; prototype; public health relevance; research clinical testing; software development; sound

DESCRIPTION (provided by applicant): This application requests funds to develop software that will facilitate the design, optimization, and assessment of novel sound processing strategies for implantable auditory prostheses. The software will be designed to interface with existing research platforms that enable diagnostic assessment and control applications. Utilities will be developed that allow users to incorporate custom signal processing and measurement modules into the software framework. Sensimetrics has completed substantial work towards the development of such software and Phase 1 work is directed at translating a current version into a comprehensive software package. Towards this end, the following specific aims must be met: 1) Expand hardware and software support for auditory prosthesis devices. The current software has been designed for use with Cochlear Corporation systems; effort will be directed towards providing support for research devices that control Advanced Bionics Corporation and MedEl Corporation systems. 2) Expand software functionality. Work is outlined to provide interfaces for developing and integrating new processing and analysis modules. 3) Improve software design. Work is outlined towards improving overall design of the software. During the first year of Phase 1, two formative evaluations of the software will be conducted in collaboration with clinical and academic partners. The first will be conducted in collaboration with Children's Hospital Boston to investigate clinically relevant measures of synchrony in bilateral cochlear implant recipients. The second formative evaluation will be conducted in collaboration with the University of Minnesota and will investigate relations between psychophysical and speech reception measures in auditory brainstem and midbrain implant recipients. During the second year, these formative evaluations will be brought into summative evaluations in which the focus will shift away from software development and into clinical evaluation. As this shift occurs, the project's focus will also shift to new academic and clinical partnerships aimed at further development of the software. The planned developments include interfacing the software with a PDA processor under development at the University of Texas at Dallas and extending the software for use in as an auditory training resource. The objective is to produce a flexible and modular framework that can be readily reconfigured for new applications. Phase 1 will deliver a prototype containing the necessary utilities that can be used flexibly for diagnostic assessment and control of auditory prostheses. PUBLIC HEALTH RELEVANCE: This application requests funds to develop software that will facilitate the design, optimization, and assessment of novel sound processing strategies for implantable auditory prostheses. The software will be designed to interface with existing research platforms that enable diagnostic assessment and control applications. This software development project is framed around two formative evaluations directed at synchronization of bilateral cochlear implants and at sound processing design for auditory brainstem and midbrain implants.

描述（由申请人提供）： 该申请要求资金开发软件，以促进植入式听觉假体的新颖声音处理策略的设计、优化和评估。该软件将设计为与现有研究平台接口，支持诊断评估和控制应用。将开发实用程序，允许用户将自定义信号处理和测量模块合并到软件框架中。 Sensimetrics 已经完成了此类软件开发的大量工作，第一阶段的工作旨在将当前版本转换为综合软件包。为此，必须满足以下具体目标： 1）扩大对听觉假体设备的硬件和软件支持。当前的软件设计用于科利耳公司的系统；将致力于为控制 Advanced Bionics Corporation 和 MedEl Corporation 系统的研究设备提供支持。 2) 扩展软件功能。概述的工作是为开发和集成新的处理和分析模块提供接口。 3）改进软件设计。概述了改进软件整体设计的工作。在第一阶段的第一年，将与临床和学术合作伙伴合作对该软件进行两次形成性评估。第一项将与波士顿儿童医院合作进行，以调查双耳人工耳蜗植入者的临床相关同步测量。第二次形成性评估将与明尼苏达大学合作进行，并将调查听觉脑干和中脑植入接受者的心理物理和言语接收测量之间的关系。在第二年，这些形成性评估将纳入总结性评估，其中重点将从软件开发转向临床评估。随着这种转变的发生，该项目的重点也将转向旨在进一步开发该软件的新的学术和临床合作伙伴关系。计划的开发包括将该软件与德克萨斯大学达拉斯分校正在开发的 PDA 处理器连接，并扩展该软件作为听觉培训资源。目标是产生一个灵活的模块化框架，可以轻松地为新应用程序重新配置。第一阶段将提供一个包含必要实用程序的原型，可灵活用于听觉假体的诊断评估和控制。 公共卫生相关性： 该申请要求资金开发软件，以促进植入式听觉假体的新颖声音处理策略的设计、优化和评估。该软件将设计为与现有研究平台接口，支持诊断评估和控制应用。该软件开发项目围绕两项形成性评估构建，旨在实现双侧耳蜗植入物的同步以及听觉脑干和中脑植入物的声音处理设计。

项目成果

Two-microphone spatial filtering improves speech reception for cochlear-implant users in reverberant conditions with multiple noise sources.

双麦克风空间滤波可改善人工耳蜗用户在具有多个噪声源的混响条件下的语音接收能力。

• 发表时间: 2014-10-20
• 作者: Goldsworthy; Raymond L
• 通讯作者: Raymond L

Correlations Between Pitch and Phoneme Perception in Cochlear Implant Users and Their Normal Hearing Peers.

人工耳蜗使用者和听力正常的同龄人的音调和音素感知之间的相关性。

• 发表时间: 2015-12
• 作者: Goldsworthy; Raymond L
• 通讯作者: Raymond L