black cohosh in Laboratory Animals for the National Toxicology Program (NTP)

国家毒理学计划 (NTP) 实验动物中的黑升麻

• 批准号: 8549359
• 负责人: MILTON D HEJTMANCIK
• 金额: $ 45.09万
• 依托单位: BATTELLE CENTERS/PUB HLTH RES & EVALUATN
• 依托单位国家: 美国
• 财政年份: 2005
• 资助国家: 美国
• 起止时间: 2005-05-01 至 2013-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8549359
• 关键词: Amenorrhea; Animals; Chemicals; Chronic; Cimicifuga racemosa; Dysmenorrhea; Goals; Human; Laboratory Animals; Life; Mus; National Toxicology Program; Perimenopause; Phase; Rattus; Symptoms; Toxic effect; Toxicity Tests; Woman; carcinogenicity; dietary supplements; hazard

The goal of this project is to evaluate the chronic toxicity and carcinogenicity of black cohosh in rats and mice exposed by gavage. widespread use by women as a dietary supplement to alleviate abnormal or painful menstruation (amenorrhea, dysmenorrhea and other conditions) and perimenopausal symptoms. 2-Year chronic gavage toxicity and carcinogenicity studies of black cohosh are in the in life phase. Keywords: toxicity, carcinogenicity, gavage, black cohosh, herbal, supplement, dietary

该项目的目标是评估黑升麻对大鼠和小鼠灌胃的慢性毒性和致癌性。被女性广泛用作膳食补充剂，以缓解月经异常或疼痛（闭经、痛经和其他病症）和围绝经期症状。黑升麻的 2 年慢性灌胃毒性和致癌性研究正处于生命阶段。 关键词：毒性、致癌性、灌胃、黑升麻、草药、补充剂、膳食