p-chloro- trifluorotoluene in Laboratory Animals for the National Toxicology

国家毒理学实验动物中的对氯三氟甲苯

• 批准号: 8429120
• 负责人: MILTON D HEJTMANCIK
• 金额: $ 45.09万
• 依托单位: BATTELLE CENTERS/PUB HLTH RES & EVALUATN
• 依托单位国家: 美国
• 财政年份: 2005
• 资助国家: 美国
• 起止时间: 2005-05-01 至 2013-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8429120
• 关键词: Animals; Breathing; Chemicals; Chronic; Drug Formulations; Goals; Human; Laboratory Animals; Life; Mus; Paint; Phase; Rattus; Solvents; Toxic effect; Toxicity Tests; Toxicology; carcinogenicity; hazard

The goal of this project is to evaluate the chronic toxicity and carcinogenicity of p-chloro-,,-trifluorotoluene (PCTFT) in rats and mice exposed by inhalation. PCTFT is a solvent in paint and coating formulations. 2-Year chronic toxicity and carcinogenicity studies of PCTFT are in the in life phase. Keywords: toxicity, carcinogenicity, inhalation, p-chloro-,,-trifluorotoluene

该项目的目标是评估吸入暴露的对氯-α,α,α-三氟甲苯（PCTFT）对大鼠和小鼠的慢性毒性和致癌性。 PCTFT 是油漆和涂料配方中的溶剂。 PCTFT 的 2 年慢性毒性和致癌性研究正处于生命周期阶段。 关键词：毒性，致癌性，吸入，对氯-α,α,α-三氟甲苯