Molecular Basis of Infectious Diseases

传染病的分子基础

• 批准号: 8318633
• 负责人: STEVEN J. NORRIS
• 金额: $ 13.31万
• 依托单位: UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON
• 依托单位国家: 美国
• 财政年份: 2005
• 资助国家: 美国
• 起止时间: 2005-09-15 至 2015-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8318633
• 关键词: Communicable Diseases; Molecular; base

DESCRIPTION (provided by applicant): The Molecular Basis of Infectious Disease (MBID) research training program is centered on 16 faculty mentors from three Houston educational institutions: the University, of Texas Health Science Center at Houston, Baylor College of Medicine, and the Texas A&M University Institute for Biosciences and Technology. In this renewal application, continued training support is requested for three Ph.D. students and eight undergraduate summer research students. The overall purpose of the MBID training program is to provide trainees 1) an optimal environment for training new scientists in the latest concepts and techniques in microbiological research; 2) a better understanding of current challenges in clinical infectious diseases; and 3) the knowledge and tools to 'bridge the gap' between basic research and clinical applications. The basis of this training grant is the Molecular Basis of Infectious Disease group, which was first formed in 1996. MBID has developed into highly interactive group of over 400 faculty, postdoctoral fellows, graduate students, and staff from the Houston area whose primary interest is in the molecular pathogenesis of bacterial infections. The 16 faculty members that form the core of this training grant have a record of high research productivity and extensive collaborations. They have mentored 178 predoctoral and postdoctoral trainees during the past ten years, and currently are mentoring 22 Ph.D. students and 25 postdoctoral fellows. The training program is based on a strong core curriculum, intensive and interactive research experiences, monthly MBID meetings, annual retreats, weekly seminars and journal clubs, and training in translational research and clinical infectious diseases. A summer research program has been established to aid in the recruitment of promising undergraduate students (and in particular underrepresented minority [URM] trainees) into careers in infectious disease research. During the initial grant period, 3 of 7 predoctoral trainees and 10 of 31 summer undergraduate trainees were URM students, thus promising continued success in this objective during the coming grant period. RELEVANCE: The major goal of this ongoing, successful training grant is to provide microbiology trainees additional knowledge in clinical infectious diseases and translational research, thereby directing research toward the more rapid resolution of important infectious disease problems. In addition, the program will continue to recruit highly qualified underrepresented minority students, increasing the proportion of underrepresented minority scientists performing research at the cutting edge of the microbiology/infectious disease interface.

描述（由申请人提供）：传染病分子基础 (MBID) 研究培训计划以来自三个休斯顿教育机构的 16 名教师导师为中心：休斯顿德克萨斯大学健康科学中心、贝勒医学院和德克萨斯大学A&M 大学生物科学与技术研究所。在此续签申请中，请求为三名博士提供持续的培训支持。学生和八名本科生暑期研究生。 MBID 培训计划的总体目的是为学员提供 1) 一个最佳环境，以培训新科学家掌握微生物研究的最新概念和技术； 2）更好地了解当前临床传染病面临的挑战； 3）“弥合基础研究和临床应用之间差距”的知识和工具。该培训资助的基础是传染病分子基础小组，该小组成立于 1996 年。MBID 已发展成为由来自休斯顿地区的 400 多名教员、博士后研究员、研究生和工作人员组成的高度互动的小组，他们的主要兴趣是细菌感染的分子发病机制。构成本次培训资助核心的 16 名教职人员拥有高研究生产力和广泛合作的记录。他们在过去十年中指导了178名博士前和博士后学员，目前正在指导22名博士生。学生和25名博士后研究员。培训计划基于强大的核心课程、强化和互动研究经验、每月 MBID 会议、年度静修、每周研讨会和期刊俱乐部，以及转化研究和临床传染病培训。已经建立了一个夏季研究计划，以帮助招募有前途的本科生（特别是代表性不足的少数族裔 [URM] 受训者）从事传染病研究职业。在最初的资助期内，7 名博士前实习生中有 3 名是 URM 学生，31 名暑期本科生中有 10 名是 URM 学生，因此有望在接下来的资助期内继续成功实现这一目标。 相关性：这项持续、成功的培训资助的主要目标是为微生物学学员提供临床传染病和转化研究方面的额外知识，从而引导研究更快地解决重要的传染病问题。此外，该项目将继续招募高素质的少数族裔学生，增加在微生物学/传染病界面前沿进行研究的少数族裔科学家的比例。