HIV/STD Prevention Program for African American Males

非裔美国男性艾滋病毒/性病预防计划

基本信息

批准号：
7810809
负责人：
Stephen B. Kennedy
金额：
$ 39.28万
依托单位：
PACIFIC INSTITUTE FOR RES AND EVALUATION
依托单位国家：
美国
项目类别：
财政年份：
2010
资助国家：
美国
起止时间：
2010-03-01 至 2013-12-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/7810809
关键词：
Accounting Acquired Immunodeficiency Syndrome African American Behavioral Biological Cessation of life Characteristics Chicago Coitus Communities Computer Assisted Data Equilibrium Ethics Evaluation Research Frequencies Funding HIV Human immunodeficiency virus test Illinois Intervention Intervention Studies Interview Kentucky Low income Mediating Minority Newly Diagnosed Outcome Participant Patient Self-Report Phase Pilot Projects Population Prevention program Prevention strategy Process Public Health Public Housing Quality of life Randomized Recruitment Activity Relative (related person)Reporting Research Research Institute Research Personnel Self Efficacy Series Sex Behavior Sexually Transmitted Diseases Side Site Target Populations United States United States National Academy of Sciences Universities Variant Youth aged arm comparison group condoms experience health disparity high risk sexual behavior informant intervention program male minority health primary outcome programs randomized trial research study secondary outcome young adult

项目摘要

DESCRIPTION (provided by the applicant): Common use of condoms by young adults across all racial/ethic groups remains a formidable public health challenge, especially for African American males (Kennedy et al., 2007a,b,c; Kennedy et al., under review). As a call to action, a collaborative team of researchers proposes to conduct a four-year behavioral-driven research study to modify, implement and evaluate the efficacy of a promising brief condom promotion program in a two-arm randomized trial among African American males 18-24 years from 12 community centers on Chicago's South Side. Accordingly, we propose the following specific aims and related set of research questions: 1. Modify, implement, and assess the efficacy of a condom promotion program for African American males. 1.1. Will participants randomly assigned to the intervention report a statistically significant increase in the frequency of condom use and decrease in unprotected sexual intercourse (primary outcomes) relative to those assigned to the comparison group? 1.2. Will the intervention produce statistically significant positive effects on secondary outcomes (e.g., condom use self-efficacy, condom use decisional balance, etc.) relative to the comparison group? 1.3. Will the secondary outcomes mediate the relationship between intervention status and condom use (the primary outcome)? 2. Assess characteristics of program implementation and its relationship to changes in behavioral outcomes. 2.1. What was the level of implementation fidelity? 2.2. How is variation in implementation fidelity related to change in primary outcomes? For a nine-month formative phase, we will conduct a series of qualitative interviews with key informants and the target population to modify our existing program. Over the next 16 months, we will recruit 520 study participants from our recruitment sites to implement the intervention and comparison programs and assess the efficacy of the intervention program on a series of primary and secondary outcomes. Assuming 30% attrition rate (n=156), we expect to collect complete outcome data via Audio Computer Assisted Self Interview (ACASI) from about 364 participants over 12-months. In addition, we will conduct biological assessment of STDs to validate participants' self-reports on sexual behaviors at all assessment points. This proposed study is an extension of a recently completed NIH-funded R21 (PI: Kennedy) to develop, implement, and pilot a brief condom promotion program for African American males (Kennedy et al., 2007a,b,c; Kennedy et al., under review). We have assembled a collaborative team of experienced investigators and research partners to successfully implement this proposed project.

描述（由申请人提供）：所有种族/民族的年轻人普遍使用安全套仍然是一个巨大的公共卫生挑战，特别是对于非裔美国男性（Kennedy 等人，2007a,b,c；Kennedy 等人，正在审核中）。作为一项行动号召，一个研究人员合作小组提议进行一项为期四年的行为驱动研究，以修改、实施和评估一项有希望的短期安全套推广计划在非裔美国男性中进行的双臂随机试验中的效果18 -24 年，来自芝加哥南区 12 个社区中心。因此，我们提出以下具体目标和相关的研究问题： 1. 修改、实施针对非裔美国男性的安全套推广计划并评估其效果。 1.1.与分配到对照组的参与者相比，随机分配到干预组的参与者是否会报告安全套使用频率的统计显着增加和无保护性交的减少（主要结果）？ 1.2.相对于对照组，干预措施是否会对次要结果（例如，安全套使用自我效能、安全套使用决策平衡等）产生统计上显着的积极影响？ 1.3.次要结果是否会调节干预状态与安全套使用（主要结果）之间的关系？ 2. 评估计划实施的特点及其与行为结果变化的关系。 2.1.实施保真度的水平如何？ 2.2.实施保真度的变化与主要结果的变化有何关系？在为期九个月的形成阶段，我们将对关键知情人和目标人群进行一系列定性访谈，以修改我们现有的计划。在接下来的16个月里，我们将从招募地点招募520名研究参与者来实施干预和比较计划，并评估干预计划对一系列主要和次要结果的有效性。假设流失率为 30% (n=156)，我们预计将在 12 个月内通过音频计算机辅助自我访谈 (ACASI) 从约 364 名参与者那里收集完整的结果数据。此外，我们还将对性传播疾病进行生物学评估，以验证参与者在所有评估点对性行为的自我报告。这项拟议的研究是最近完成的 NIH 资助的 R21（PI：Kennedy）的延伸，旨在为非裔美国男性制定、实施和试点一项简短的安全套推广计划（Kennedy 等人，2007a,b,c；Kennedy 等人） .，正在审查中）。我们组建了一支由经验丰富的研究人员和研究合作伙伴组成的协作团队，以成功实施该拟议项目。