Pilot Project

试点项目

• 批准号: 8535667
• 负责人: ALINNE Z BARRERA
• 金额: $ 3.4万
• 依托单位: UNIVERSITY OF TEXAS HLTH SCIENCE CENTER
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至 2015-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8535667
• 关键词: California; Cancer Research Network; Cessation Research; Control Groups; Data; Doctor of Philosophy; Electronic Mail; Elements; Enrollment; Ensure; Evidence based intervention; Faculty; Gender; Goals; Hispanics; Internet; Intervention; Interview; Language; Latino; Lead; Mails; Measures; Methods; Moods; National Cancer Institute; Participant; Patient Self-Report; Pilot Projects; Prevalence; Publishing; Radio; Randomized; Randomized Controlled Trials; Recruitment Activity; Research; Sampling; San Francisco; Site; Smoker; Smoking; Surveys; Telephone; Testing; Time; United States Public Health Service; Universities; arm; design; efficacy trial; evidence base; follow-up; group intervention; member; post-doctoral training; professor; smoking cessation; success; trial comparing; virtual; web site

The primary goal of this Redes En Accidn pilot proposal is to canry out a randomized controlled trial (RCT) comparing quit rates of a Spanish/English stop smoking Web site to those of a no-lnten/enfion control. The University of California, San Francisco (UCSF) Stop Smoking research Web site has enrolled a diverse, internafional sample of more than 47,000 smokers into several randomixed trials since 2000. However, we have not included a no-intervention condition in these trails to date. Our published absfinence rates at one year are 20%, but obtaining evidence that our intervenfions yield higher absfinence rates than a no-intervenfion control is the next logical step. Furthermore, although our Web site was designed in English and Spanish, our success in attracting the U.S. Hispanic/Latino (HL) population in either language has been limited, so this project only will recruit HL smokers and add new recruitment methods to do so. The study will randomize HL participants to one of two condifions, an inten/enfion condition ("immediate") and a no-intervenfion control ("delayed"). For the control, a 6-month "Delayed" treatment condition (DC) will inform participants that we are tesfing whether HL smokers who are motivated enough to seek Internet information on smoking cessafion can quit on their own at the same rate as smokers who are given access to an interacfive stop smoking Web site. We will provide them a basic online smoking cessafion packet(1) from the U.S. Public Health Service (USPHS). For our intervention, the "Immediate" treatment condition (IC) is the UCSF Spanish/English Stop Smoking research Web site (vwvw.stoDsmokina.ucsf.edu) that provides smokers all elements tested in eariier trials: 1) a Web version of a National Cancer Institute-designated evidence-based intervenfion, the Guia para Dejarde Fumar2; 2) e-mail reminders to return to the site fimed to individually set quit dates; 3) a mood management smoking cessafion intervenfion; and 4) a virtual group (an asynchronous bullefin board designed to let participants provide mutual support). All IC participants also will receive the USPHS cessafion packet from the DC control to ensure that the interactive Web site is the only difference between the condifions. We will randomize 608 HL smokers in English or Spanish stratified by gender within language group. Participants will be followed at 1, 3, and 6 months after randomizafion to obtain self-reported prolonged absfinence and 7- and 30-day time point prevalence rates. E-mail reminders will be sent to remind participants to return to the site to complete follow-up surveys. The main comparison measure will be cessafion at 6 months from original randomization. DC participants will be able to access the interactive site after finishing the 6-month follow-up. We plan to attract Spanish-speaking HL participants to our Web site using Spanish-language TV and radio interviews and PSAs, Spanish-language Google ads and networking with U.S. cessation groups.

此重复的主要目标是，将西班牙/英语停止吸烟网站与非lnten/enfion控制的戒烟率进行比较的随机对照试验（RCT）进行挑剔。加利福尼亚大学旧金山大学（UCSF）停止吸烟研究网站已将超过47,000名吸烟者的多样化的内部样本招募到自2000年以来的几项随机试验中。但是，迄今为止，我们还没有在这些步道中不包括不干预条件。我们发表的一年的可节省率 为20％，但获得证据表明我们的干预措施比无中心控制是下一个逻辑步骤。此外，尽管我们的网站是用英语和西班牙语设计的，但我们在吸引美国西班牙裔/拉丁美洲人（HL）人群中以两种语言的成功而设计的。这项研究将将HL参与者随机为两种条件之一，即进气条件（“立即”）和无中裂的控制 （“延迟”）。对于控制，一个为期6个月的“延迟”治疗条件（DC）将通知参与者，我们是否正在提出足够动力的HL吸烟者，以寻求有关吸烟Cessafion的Internet信息的HL吸烟者是否可以自行戒烟，以与获得间隔间停止吸烟网站的吸烟者相同的速度。 我们将为他们提供来自美国公共卫生服务（USPHS）的基本在线吸烟包（1）。 为了进行干预，“直接”治疗条件（IC）是UCSF西班牙语/英语停止吸烟研究网站（vwvw.stodsmokina.ucsf.edu），它为吸烟者提供了在Eariier试验中测试的所有元素：1）基于国家癌症研究所的网络版本，基于国家癌症研究所的网络版本，基于基于证明的基于证明的基于基于证据的毒品。 2）发送电子邮件提醒返回到fim的站点，以单独设置戒烟日期； 3）一种情绪管理吸烟污水处理； 4）一个虚拟组（一个异步的Bullefin板，旨在让参与者提供相互支持）。所有IC参与者还将从The DC控制以确保交互式网站是条件之间的唯一区别。我们将以语言组中的性别分层的英语或西班牙语进行608 hl吸烟者或西班牙语。随机化后1、3和6个月，参与者将获得自我报告的长时间节省和7天和30天的时间点的患病率。将发送电子邮件提醒，以提醒参与者返回网站以完成后续调查。主要的比较度量将是原始随机分组6个月后的Cessafion。完成为期6个月的随访后，DC参与者将能够访问交互式站点。 我们计划使用西班牙语电视和广播采访，PSA，西班牙语Google广告以及与美国戒烟组的网络吸引讲西班牙语的HL参与者进入我们的网站。