Tracking Symptoms during Chemotherapy via Online Patient Self-reporting

通过在线患者自我报告跟踪化疗期间的症状

基本信息

批准号：
7922782
负责人：
ETHAN M. BASCH
金额：
$ 10万
依托单位：
SLOAN-KETTERING INST CAN RESEARCH
依托单位国家：
美国
项目类别：
财政年份：
2009
资助国家：
美国
起止时间：
2009-09-01 至 2011-08-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/7922782
关键词：
Accounting Address Administrative Efficiency Adverse event Area Award Behavior Behavior Therapy Cancer Center Cancer Patient Caring Client satisfaction Clinical Clinical Informatics Clinical Research Clinical Trials Common Terminology Criteria for Adverse Events Communication Data Data Collection Data Quality Detection Documentation Drug toxicity Early Diagnosis Electronics Ensure Evaluation Exposure to Feasibility Studies Fostering Funding Goals Gold Health Services Health Services Research Industry Internet K-Series Research Career Programs Life Malignant Neoplasms Measures Medical Oncology Memorial Sloan-Kettering Cancer Center Mentors Methods Minority Modeling Monitor Operative Surgical Procedures Outcome Outcomes Research Participant Patient Outcomes Assessments Patient Self-Report Patients Process Quality of life Questionnaires Randomized Controlled Clinical Trials Reporting Research Research Ethics Committees Research Personnel Research Support Screening procedure Series Serious Adverse Event Symptoms Testing Time Toxic effect Treatment outcome Work base cancer care cancer therapy career career development chemotherapy design experience health related quality of life improved instrument new technology oncology patient oriented patient safety programs response routine care skills symptom management tool treatment trial

项目摘要

DESCRIPTION (provided by applicant): This proposal envisions a comprehensive plan for the career development of Dr. Ethan Basch in cancer outcomes research. Through mentored research, coursework, and independent study, Dr. Basch will develop collaborative relationships and methodologic skills to support his research agenda in clinical informatics and patient symptom management. This work focuses on the use of novel technologies to improve symptom monitoring during cancer care and trials, specifically through the evaluation of patient- centered treatment models which integrate patient reported outcomes (PROs). Currently, it is not standard to use patients' own self-reported symptom information to monitor cancer care. Rather, clinicians are relied upon to elicit, filter and report this information - an approach which is mandated in NCI and industry-sponsored trials. This stands in contrast to quality of life or symptom research, in which PROs are standard. The overall objective of this research program is to explore the application of patient self-reporting to symptom monitoring in oncology treatment, as a possible new paradigm. The specific aims are: 1) to assess the feasibility of routinely collecting symptom PROs via the web during cancer care and trials; 2) to measure the relationship between patient and clinician symptom reporting using the standard U.S. instrument for this purpose, the NCI's Common Terminology Criteria for Adverse Events (CTCAE); and 3) to evaluate the impact of patient self-reporting on clinical and administrative outcomes. This agenda will be accomplished through a series of IRB-approved studies Dr. Basch has designed and is systematically conducting at Memorial Sloan-Kettering Cancer Center, as well as nested in multicenter NCI and industry-sponsored clinical trials. RELEVANCE: Patient self-reporting may increase the efficiency of clinical operations, foster early detection of serious adverse events, and improve patient satisfaction. Engaging patients as active participants in research and in their own care conveys the message that treatment tolerance is an important endpoint. This work will help determine how new technologies may be deployed to improve traditional models of care.

描述（由申请人提供）：该提案为 Ethan Basch 博士在癌症结果研究领域的职业发展制定了全面的计划。通过指导研究、课程作业和独立研究，Basch 博士将发展合作关系和方法技能，以支持他在临床信息学和患者症状管理方面的研究议程。这项工作的重点是使用新技术来改善癌症护理和试验期间的症状监测，特别是通过评估以患者为中心的治疗模型，其中整合了患者报告的结果（PRO）。目前，使用患者自我报告的症状信息来监测癌症治疗并不标准。相反，临床医生需要引出、过滤和报告这些信息——NCI 和行业赞助的试验中强制采用这种方法。这与生活质量或症状研究形成鲜明对比，在这些研究中，PRO 是标准的。该研究项目的总体目标是探索患者自我报告在肿瘤治疗中症状监测中的应用，作为一种可能的新范例。具体目标是： 1) 评估在癌症护理和试验期间通过网络定期收集症状 PRO 的可行性； 2) 使用美国标准工具 NCI 的不良事件通用术语标准 (CTCAE) 来衡量患者和临床医生症状报告之间的关系； 3) 评估患者自我报告对临床和管理结果的影响。该议程将通过 Basch 博士设计并在纪念斯隆-凯特琳癌症中心系统地进行的一系列 IRB 批准的研究以及嵌套在多中心 NCI 和行业赞助的临床试验中来完成。相关性：患者自我报告可以提高临床操作的效率，促进严重不良事件的早期发现，并提高患者满意度。让患者积极参与研究和自己的护理传达了这样的信息：治疗耐受性是一个重要的终点。这项工作将有助于确定如何部署新技术来改进传统的护理模式。