ACTIVE SITE DYNAMICS OF SUBTILISIN CARLSBERG BY SDSL ESR

通过 SDSL ESR 分析枯草杆菌蛋白酶嘉士伯的活性位点动态

• 批准号: 8364001
• 负责人: ZHICHUN LIANG
• 金额: $ 1.32万
• 依托单位: CORNELL UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-09-01 至 2012-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8364001
• 关键词: Active Sites; Disease model; Frequencies; Funding; Grant; Least-Squares Analysis; Modeling; National Center for Research Resources; Principal Investigator; Research; Research Infrastructure; Resources; Services; Source; Structure; Subtilopeptidase A; Technology; United States National Institutes of Health; base; cost; programs; web site

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. Primary support for the subproject and the subproject's principal investigator may have been provided by other sources, including other NIH sources. The Total Cost listed for the subproject likely represents the estimated amount of Center infrastructure utilized by the subproject, not direct funding provided by the NCRR grant to the subproject or subproject staff. NLSL is a non linear least squares program for fitting CW spectra based on microscopically order but macroscopically disorder (MOMD) model. NLSL.SRLS is a non linear least squares program for fitting multi-frequency CW spectra based on slowly relaxing local structure (SRLS) model A service request was received from Dr Vibha Bansal on the usage of the NLSL and NLSL.SRSL programs from ACERT website to study active site dynamics of Subtilisin Carlsberg by SDSL ESR.

该子项目是利用资源的众多研究子项目之一 由 NIH/NCRR 资助的中心拨款提供。子项目的主要支持 并且子项目的首席研究员可能是由其他来源提供的， 包括其他 NIH 来源。 子项目可能列出的总成本 代表子项目使用的中心基础设施的估计数量， NCRR 赠款不直接向子项目或子项目工作人员提供资金。 NLSL 是一种非线性最小二乘程序，用于基于微观有序但宏观无序 (MOMD) 模型拟合 CW 光谱。 NLSL.SRLS 是一种基于缓慢松弛局部结构 (SRLS) 模型的非线性最小二乘程序，用于拟合多频 CW 频谱已收到 Vibha Bansal 博士关于使用 ACERT 网站上的 NLSL 和 NLSL.SRSL 程序的服务请求通过 SDSL ESR 研究枯草杆菌蛋白酶 Carlsberg 的活性位点动态。