DYNAMIC EXCHANGE BETWEEN TWO CONFORMERS OF A PROTEIN

蛋白质两个构象体之间的动态交换

• 批准号: 8364008
• 负责人: ZHICHUN LIANG
• 金额: $ 0.48万
• 依托单位: CORNELL UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-09-01 至 2012-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8364008
• 关键词: Electronic Mail; Frequencies; Funding; Grant; Hand; Instruction; Modeling; National Center for Research Resources; Principal Investigator; Protein Dynamics; Proteins; Research; Research Infrastructure; Resources; Services; Simulate; Source; Structure; Technology; United States National Institutes of Health; base; computer program; conformer; cost; programs; web site

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. Primary support for the subproject and the subproject's principal investigator may have been provided by other sources, including other NIH sources. The Total Cost listed for the subproject likely represents the estimated amount of Center infrastructure utilized by the subproject, not direct funding provided by the NCRR grant to the subproject or subproject staff. NLSL.SRLS.EXCH is a computer program for simulating multi-frequency CW spectra based on slowly relaxing local structure (SRLS) model with dynamic exchange. A service request was received from Michael D. Bridges on the usage of the NLSL.SRLS.EXCH program from ACERT website to study protein dynamics undergoing conformational exchange. Hand on instruction has been given to him via emails.

该副本是利用资源的众多研究子项目之一 由NIH/NCRR资助的中心赠款提供。对该子弹的主要支持 而且，副投影的主要研究员可能是其他来源提供的 包括其他NIH来源。 列出的总费用可能 代表subproject使用的中心基础架构的估计量， NCRR赠款不直接向子弹或副本人员提供的直接资金。 NLSL.SRLS.EXCH是一种计算机程序，用于模拟具有动态交换的慢速放松本地结构（SRLS）模型，以模拟多频CW Spectra。 Michael D. Bridges收到了有关NLSL.SRLS.EXCH计划的使用，从Acert网站使用构象交换的蛋白质动力学。通过电子邮件向他提供了指导。