DYNAMIC EXCHANGE BETWEEN TWO CONFORMERS OF A PROTEIN

蛋白质两个构象体之间的动态交换

• 批准号: 8364008
• 负责人: ZHICHUN LIANG
• 金额: $ 0.48万
• 依托单位: CORNELL UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-09-01 至 2012-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8364008
• 关键词: Electronic Mail; Frequencies; Funding; Grant; Hand; Instruction; Modeling; National Center for Research Resources; Principal Investigator; Protein Dynamics; Proteins; Research; Research Infrastructure; Resources; Services; Simulate; Source; Structure; Technology; United States National Institutes of Health; base; computer program; conformer; cost; programs; web site

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. Primary support for the subproject and the subproject's principal investigator may have been provided by other sources, including other NIH sources. The Total Cost listed for the subproject likely represents the estimated amount of Center infrastructure utilized by the subproject, not direct funding provided by the NCRR grant to the subproject or subproject staff. NLSL.SRLS.EXCH is a computer program for simulating multi-frequency CW spectra based on slowly relaxing local structure (SRLS) model with dynamic exchange. A service request was received from Michael D. Bridges on the usage of the NLSL.SRLS.EXCH program from ACERT website to study protein dynamics undergoing conformational exchange. Hand on instruction has been given to him via emails.

该子项目是利用资源的众多研究子项目之一 由 NIH/NCRR 资助的中心拨款提供。子项目的主要支持 并且子项目的首席研究员可能是由其他来源提供的， 包括其他 NIH 来源。 子项目可能列出的总成本 代表子项目使用的中心基础设施的估计数量， NCRR 赠款不直接向子项目或子项目工作人员提供资金。 NLSL.SRLS.EXCH 是一个基于具有动态交换的慢松弛局部结构 (SRLS) 模型来模拟多频 CW 频谱的计算机程序。收到 Michael D. Bridges 的服务请求，要求使用 ACERT 网站的 NLSL.SRLS.EXCH 程序来研究进行构象交换的蛋白质动力学。已通过电子邮件向他提供了实际操作指导。