TOWARD TOTAL STRUCTURAL ANALYSIS OF CARDIOLIPINS: MULTIPLE-STAGE LINEAR ION-TRAP

心磷脂的总结构分析：多级线性离子阱

• 批准号: 8361439
• 负责人: JOHN W TURK
• 金额: $ 4.32万
• 依托单位: WASHINGTON UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-01-01 至 2011-12-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8361439
• 关键词: Cardiolipins; Fatty Acids; Funding; Glycerol; Grant; Ions; Location; Mass Spectrum Analysis; National Center for Research Resources; Principal Investigator; Research; Research Infrastructure; Resources; Source; Staging; United States National Institutes of Health; Vertebral column; biomedical resource; cost; pi bond

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. Primary support for the subproject and the subproject's principal investigator may have been provided by other sources, including other NIH sources. The Total Cost listed for the subproject likely represents the estimated amount of Center infrastructure utilized by the subproject, not direct funding provided by the NCRR grant to the subproject or subproject staff. ESI multiple-stage linear ion-trap (LIT) mass spectrometric approaches for a near-complete structural characterization of cardiolipins (CLs), including identification of the fatty acyl substituents, assignment of the fatty acid substituents on the glycerol backbone, and location of the double-bond(s) or cyclopropyl group along the fatty acid chain are described.

该副本是利用资源的众多研究子项目之一 由NIH/NCRR资助的中心赠款提供。对该子弹的主要支持 而且，副投影的主要研究员可能是其他来源提供的 包括其他NIH来源。 列出的总费用可能 代表subproject使用的中心基础架构的估计量， NCRR赠款不直接向子弹或副本人员提供的直接资金。 ESI多个阶段线性离子陷阱（LIT）质谱方法，用于对心脏脂蛋白的几乎完整结构表征（CLS），包括鉴定脂肪酰基取代基，在甘油骨架上的脂肪酸取代基的分配以及双键（S）或环甲基沿脂肪酸链的位置。