3D RADIAL PIPELINE FOR RECONSTRUCTION OF CLINICAL 129XE IMAGES

用于重建临床 129XE 图像的 3D 径向管道

• 批准号: 8363198
• 负责人: Bastiaan Driehuys
• 金额: $ 1.23万
• 依托单位: DUKE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-07-01 至 2012-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8363198
• 关键词: Archives; Blood; Clinical; Code; Data; Development; Ensure; Environmental air flow; Funding; Grant; Image; Lung; Microscopy; National Center for Research Resources; Physiologic pulse; Principal Investigator; Radial; Research; Research Infrastructure; Resources; Slice; Source; Tissues; United States National Institutes of Health; Work; Writing; Xenon; cost; image archival system; interest; programs; reconstruction

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. Primary support for the subproject and the subproject's principal investigator may have been provided by other sources, including other NIH sources. The Total Cost listed for the subproject likely represents the estimated amount of Center infrastructure utilized by the subproject, not direct funding provided by the NCRR grant to the subproject or subproject staff. We are currently conducting clinical imaging of hyperpolarized 129Xe. Historically we have used multi-slice GRE sequences that reconstruct on the scanner. However, we are now becoming increasingly interested in using radial acquisition and reconstruction for this work. Hence, we are becoming increasingly reliant on the data reconstruction and image archiving pipeline maintained by the CIVM staff. Our ongoing program will be working to produce isotropic 129Xe ventilation images as well as images of 129Xe dissolved in pulmonary blood and tissues. On-going pulse sequence development is also being done to acquire both of these images simultaneously during a single breath hold. This work makes use of the CIVM infrastructure, but should require no further support. This project form is being written to document usage of the CIVM infrastructure and to ensure that a project code is available for reconstructing and archiving xenon images.

该副本是利用资源的众多研究子项目之一 由NIH/NCRR资助的中心赠款提供。对该子弹的主要支持 而且，副投影的主要研究员可能是其他来源提供的 包括其他NIH来源。 列出的总费用可能 代表subproject使用的中心基础架构的估计量， NCRR赠款不直接向子弹或副本人员提供的直接资金。 我们目前正在进行超极化129xE的临床成像。从历史上看，我们使用了在扫描仪上重建的多块GRE序列。但是，我们现在对在这项工作中使用径向采集和重建变得越来越感兴趣。因此，我们越来越依赖于CIVM员工维护的数据重建和图像归档管道。我们正在进行的计划将致力于产生各向同性的129XE通风图像以及溶解在肺血和组织中的129 Xe的图像。在单次呼吸期间，也正在进行持续的脉冲序列开发以同时获取这两个图像。这项工作利用了CIVM基础设施，但不应需要进一步的支持。该项目表格正在编写以记录CIVM基础架构的使用情况，并确保可用于重建和存档XENON图像的项目代码。