3D RADIAL PIPELINE FOR RECONSTRUCTION OF CLINICAL 129XE IMAGES

用于重建临床 129XE 图像的 3D 径向管道

• 批准号: 8363198
• 负责人: Bastiaan Driehuys
• 金额: $ 1.23万
• 依托单位: DUKE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-07-01 至 2012-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8363198
• 关键词: Archives; Blood; Clinical; Code; Data; Development; Ensure; Environmental air flow; Funding; Grant; Image; Lung; Microscopy; National Center for Research Resources; Physiologic pulse; Principal Investigator; Radial; Research; Research Infrastructure; Resources; Slice; Source; Tissues; United States National Institutes of Health; Work; Writing; Xenon; cost; image archival system; interest; programs; reconstruction

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. Primary support for the subproject and the subproject's principal investigator may have been provided by other sources, including other NIH sources. The Total Cost listed for the subproject likely represents the estimated amount of Center infrastructure utilized by the subproject, not direct funding provided by the NCRR grant to the subproject or subproject staff. We are currently conducting clinical imaging of hyperpolarized 129Xe. Historically we have used multi-slice GRE sequences that reconstruct on the scanner. However, we are now becoming increasingly interested in using radial acquisition and reconstruction for this work. Hence, we are becoming increasingly reliant on the data reconstruction and image archiving pipeline maintained by the CIVM staff. Our ongoing program will be working to produce isotropic 129Xe ventilation images as well as images of 129Xe dissolved in pulmonary blood and tissues. On-going pulse sequence development is also being done to acquire both of these images simultaneously during a single breath hold. This work makes use of the CIVM infrastructure, but should require no further support. This project form is being written to document usage of the CIVM infrastructure and to ensure that a project code is available for reconstructing and archiving xenon images.

该子项目是利用资源的众多研究子项目之一 由 NIH/NCRR 资助的中心拨款提供。子项目的主要支持 并且子项目的首席研究员可能是由其他来源提供的， 包括其他 NIH 来源。 子项目可能列出的总成本 代表子项目使用的中心基础设施的估计数量， NCRR 赠款不直接向子项目或子项目工作人员提供资金。 我们目前正在进行超极化 129Xe 的临床成像。历史上，我们使用在扫描仪上重建的多切片 GRE 序列。然而，我们现在对使用径向采集和重建来完成这项工作越来越感兴趣。因此，我们越来越依赖 CIVM 工作人员维护的数据重建和图像归档管道。我们正在进行的计划将致力于生成各向同性 129Xe 通气图像以及溶解在肺血液和组织中的 129Xe 图像。正在进行的脉冲序列开发也正在进行中，以便在一次屏气期间同时获取这两个图像。这项工作利用了 CIVM 基础设施，但不需要进一步的支持。编写此项目表格是为了记录 CIVM 基础设施的使用情况，并确保项目代码可用于重建和存档氙气图像。