MOLECULAR AND CELLULAR IMMUNOLOGY CORE

分子和细胞免疫学核心

• 批准号: 8360752
• 负责人: George S Hui
• 金额: $ 31.37万
• 依托单位: UNIVERSITY OF HAWAII AT MANOA
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-07-01 至 2012-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8360752
• 关键词: Biological Assay; Cell Separation; Cellular Immunology; Centers of Research Excellence; Communities; Development; Educational workshop; Emerging Communicable Diseases; Equipment; Extramural Activities; Faculty; Flow Cytometry; Funding; Grant; Health Services Research; Immune; Infectious Diseases Research; Mentors; Methods; Mission; Molecular Immunology; National Center for Research Resources; Principal Investigator; Productivity; Publications; Research; Research Infrastructure; Research Personnel; Resources; Schedule; Services; Source; Students; Techniques; Training; Training and Education; United States National Institutes of Health; Universities; base; cost; experience; improved; meetings; novel; research and development

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. Primary support for the subproject and the subproject's principal investigator may have been provided by other sources, including other NIH sources. The Total Cost listed for the subproject likely represents the estimated amount of Center infrastructure utilized by the subproject, not direct funding provided by the NCRR grant to the subproject or subproject staff. By building on an equipment grant to purchase a research-dedicated FACSCalibur flow cytometer in 2001, COBRE funds were leveraged to develop core services in flow cytometry and other immune-based assays, as part of the overall Technical Support Core during the initial COBRE grant period. High demand for all support services have prompted the proposed development of a stand-alone core for molecular and cellular immunology. The new grant period will witness the maturation of this core to meet the mission of service, research and development, and education and training. As the sole resource for flow cytometry, cell sorting and state-of-the-art immunological services in the westernmost IDeA state, the Molecular and Cellular Immunology Core will accelerate research productivity, in terms of publications and extramural funding. Emphasis will also be applied to developing new or customized immunological methods for COBRE Investigators and other Core users. In addition, regularly scheduled training sessions will be held to enrich the educational and mentoring experience for COBRE Investigators and other faculty and students across the University and broader research community. It is envisioned that by centralizing immunological services and resources to this Core, COBRE Investigators and other researchers will be more efficiently served and the use of expensive equipment will be maximized. Specific Aim 1. Enhance support and services in molecular and cellular immunology. Specific Aim 2. Develop improved immunological assays and explore novel applications for existing techniques. Specific Aim 3. Develop and implement training and education workshops in molecular and cellular immunology.

该子项目是利用资源的众多研究子项目之一 由 NIH/NCRR 资助的中心拨款提供。子项目的主要支持 并且子项目的首席研究员可能是由其他来源提供的， 包括其他 NIH 来源。 子项目可能列出的总成本 代表子项目使用的中心基础设施的估计数量， NCRR 赠款不直接向子项目或子项目工作人员提供资金。 通过 2001 年购买研究专用 FACSCalibur 流式细胞仪的设备拨款，COBRE 资金被用于开发流式细胞术和其他基于免疫的检测的核心服务，作为最初 COBRE 拨款期间整体技术支持核心的一部分。对所有支持服务的高需求促使提议开发分子和细胞免疫学的独立核心。新的资助期将见证这一核心的成熟，以履行服务、研发、教育和培训的使命。 作为 IDeA 最西端的流式细胞术、细胞分选和最先进的免疫学服务的唯一资源，分子和细胞免疫学核心将在出版物和外部资金方面提高研究生产力。重点还将应用于为 COBRE 研究者和其他核心用户开发新的或定制的免疫学方法。此外，还将定期举办培训课程，以丰富 COBRE 研究人员以及大学和更广泛的研究界的其他教职员工和学生的教育和指导经验。 预计通过将免疫学服务和资源集中到该核心，COBRE 研究人员和其他研究人员将得到更有效的服务，并且昂贵设备的使用将得到最大化。 具体目标 1.加强分子细胞免疫学支持和服务。 具体目标 2. 开发改进的免疫学测定方法并探索现有技术的新应用。 具体目标 3. 制定并实施分子和细胞免疫学培训和教育讲习班。