STRUCTURAL BASIS OF AMBLYOPIA & STRABISMUS

弱视的结构基础

• 批准号: 8357238
• 负责人: JONATHON C HORTON
• 金额: $ 2.77万
• 依托单位: UNIVERSITY OF CALIFORNIA AT DAVIS
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-05-01 至 2012-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8357238
• 关键词: Amblyopia; Animal Model; Animals; California; Exotropia; Eye; Eye Movements; Funding; Grant; Human; Infant; Macaca; Measures; Medial; National Center for Research Resources; Primates; Principal Investigator; Research; Research Infrastructure; Resources; Smooth Pursuit; Source; Strabismus; United States National Institutes of Health; base; cost; gaze; preference; sample fixation

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. Primary support for the subproject and the subproject's principal investigator may have been provided by other sources, including other NIH sources. The Total Cost listed for the subproject likely represents the estimated amount of Center infrastructure utilized by the subproject, not direct funding provided by the NCRR grant to the subproject or subproject staff. The objective of this project is to develop an animal model of human strabismus. To provide an animal model of human exotropia, a free tenotomy was preformed in infant macaques of the medial recti. When the animals were old enough to record eye movements with video eye trackers, we measured their ductions, ocular alignment, comitance, smooth pursuit, fixation preference, and gaze stability.

该副本是利用资源的众多研究子项目之一 由NIH/NCRR资助的中心赠款提供。对该子弹的主要支持 而且，副投影的主要研究员可能是其他来源提供的 包括其他NIH来源。 列出的总费用可能 代表subproject使用的中心基础架构的估计量， NCRR赠款不直接向子弹或副本人员提供的直接资金。 该项目的目的是开发人类斜视的动物模型。 为了提供人类外侧的动物模型，在内侧直肠的婴儿猕猴中预先形成了自由替骨切开术。 当动物年龄足够大，可以通过视频痕迹记录眼睛的动作，我们测量了它们的刚性，眼对准，；