ROLE OF CEREBELLAR PARALLEL FIBERS IN SACCADE ACCURACY

小脑平行纤维在扫视准确性中的作用

• 批准号: 8357601
• 负责人: FARREL R ROBINSON
• 金额: $ 15.66万
• 依托单位: UNIVERSITY OF WASHINGTON
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-05-01 至 2012-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8357601
• 关键词: Axon; Cerebellum; Deceleration; Eye Movements; Fiber; Funding; Goals; Grant; National Center for Research Resources; Primates; Principal Investigator; Research; Research Infrastructure; Resources; Role; Saccades; Signal Transduction; Source; System; Testing; Travel; United States National Institutes of Health; cost; oculomotor; relating to nervous system

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. Primary support for the subproject and the subproject's principal investigator may have been provided by other sources, including other NIH sources. The Total Cost listed for the subproject likely represents the estimated amount of Center infrastructure utilized by the subproject, not direct funding provided by the NCRR grant to the subproject or subproject staff. The goal of this research is to 1) describe how the cerebellum transforms incoming eye movement signals into the signals that it sends to the oculomotor system and 2) describe how signals from the cerebellum contribute to the neural commands for eye movements. For goal 1 we tested the proposal that a signal critical to saccade accuracy travels across the midline of the cerebellum in the axons called parallel fibers (p-fibers). We found that cutting p-fibers that cross the midline does not disrupt saccade deceleration and rejected the proposal.

该副本是利用资源的众多研究子项目之一 由NIH/NCRR资助的中心赠款提供。对该子弹的主要支持 而且，副投影的主要研究员可能是其他来源提供的 包括其他NIH来源。 列出的总费用可能 代表subproject使用的中心基础架构的估计量， NCRR赠款不直接向子弹或副本人员提供的直接资金。 这项研究的目的是：1）描述小脑如何将传入的眼动信号转化为传递到眼动系统的信号，并描述2）描述小脑信号如何为眼睛运动的神经命令做出贡献。 对于目标1，我们测试了以下提议：扫视精度至关重要的信号在称为平行纤维（P纤维）的轴突中的小脑中线上行驶。 我们发现，横穿中线的p纤维不会破坏扫视减速并拒绝该提议。