Electro-optic adaptive eyeglass for correction of presbyopia

矫正老花眼的电光自适应眼镜

• 批准号: 8278640
• 负责人: Guoqiang Li
• 金额: $ 36.48万
• 依托单位: OHIO STATE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-09-01 至 2015-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8278640
• 关键词: Adopted; Area; Astigmatism; Automobile Driving; Boxing; Caliber; Caring; Clinical Research; Computers; Contact Lenses; Contrast Sensitivity; Devices; Distant; Dizziness; Electronics; Elements; Eye; Eyeglasses; Feedback; Goals; Human; Intraocular lens implant device; Light; Manuals; Measures; Methods; Mono-S; Myopia; Ophthalmologist; Optics; Patients; Performance; Phase; Population; Presbyopia; Quality of life; Reaction Time; Reading; Refractive Errors; Research; Scanning; System; Techniques; Time; Vision; Visual Acuity; Visual impairment; abstracting; adaptive optics; age related; bioimaging; cost; cost effective; design; gaze; improved; lens; light weight; liquid crystal; meetings; novel; novel strategies; operation; practical application; prototype; simulation; visual performance; voltage

Electro-optic adaptive eyeglass for correction of presbyopia Abstract Presbyopia is an age-related loss of accommodation of the human eye that manifests itself as inability to shift focus from distant to near objects. More than 90% of the people over 45 need correction of presbyopia. The conventional corrective lenses (bifocal, trifocal) have been around for more than 200 years and have some drawbacks. They have a limited field of view for each vision task, requiring user to gaze down to accomplish near vision and in some cases causing dizziness and discomfort. Some users need three different eyeglasses for reading, computer, and driving. Progressive lenses cause some distortion. Recently we have demonstrated switchable diffractive liquid crystal (LC) lens with binary ON and OFF states. In the proposed project, our goal is to develop a tunable, low-cost electro-optic lens with continuous focusing powers and high optical performance for near-, intermediate-, and distance vision. The whole aperture with the same power is used for each vision task. Such a device may have revolutionary impact on the field of vision care. Existing LC lenses have an aperture of 10-15 mm, and the power can only be switched between plano and 1 diopter (D) (or 2D). The driver box is 4¿4¿2 cm3, which is bulky. They are not suitable for practical ophthalmic applications. In this study, we will develop a novel, high performance, cost-effective varifocal LC lens with a compact electronic driver and controller. The focusing power of the lens can be continuously tuned from plano to +4D by applied voltages. This range covers the typical add powers needed for presbyopes, and it allows almost all patients to use the same lens. We will fabricate lenses with an aperture around 40mm, which satisfies the requirement for practical applications. The light efficiency will be close to 100%. These three specifications have not been met before. We will design a novel closed-loop driver circuit with good reliability and high power efficiency. In addition, we will develop a minicontroller that allows change of the focus power by simply pressing a button, which is practical and reliable; in the second phase of this project, we will develop a prototype of the eyeglass that allows autofocus function. The size of the driver will be only 5¿5¿2 mm3. Clinical studies will be performed to assess how the wearers function and perceive the new spectacles. This kind of lens is promising to become an alternative of conventional area division multi-focal spectacle lenses used by presbyopes. They may have the potential of revolutionizing the field of presbyopia correction. The new eyeglass will significantly improve the quality of life for a large population. Applications can be extended to fields where varifocal lens elements with low operation voltages, relatively large diameters and fast response time are desirable. For example, a single lens of this kind can be used as a new phoropter to measure the refractive errors and visual acuity and for rapid depth scanning in three-dimensional biomedical imaging. Correction of low vision with high quality optics in the periphery will also have high impact. This would be our next focus of research.

用于校正长老会的电形自适应眼镜 抽象的 长老会是与年龄相关的人眼住宿的丧失，表现为 无法将重点从遥远的物体转移到近对象。超过90％的人超过45人需要 纠正长老会。常规矫正镜片（双焦点，三灶）已经 约200多年来有一些缺点。他们的视野有限 对于每个视觉任务 引起头晕和不适。一些用户需要三种不同的眼镜才能阅读， 电脑和驾驶。进行性镜头会导致一些失真。最近我们有 具有可切换的衍射液体晶体（LC）透镜，并具有二进制的状态。在 拟议的项目，我们的目标是与 近乎，中间和 远程视觉。每个视觉任务都使用具有相同功率的整个光圈。这样的 设备可能会对视力护理领域产生革命性的影响。 现有的LC镜头的光圈为10-15毫米，并且功率只能切换 在平面和1个屈光度（D）（或2D）之间。驾驶员箱为4€2 cm3，这很大。他们 不适合实用的眼科应用。在这项研究中，我们将开发一部小说 高性能，具有成本效益的Varifocal LC镜头，带有紧凑的电子驱动器和 控制器。镜头的聚焦能力可以通过平面连续调节到 +4D 施加电压。此范围涵盖了长老会所需的典型添加功率，它 允许几乎所有患者使用相同的镜头。我们将用光圈制造镜片 大约40mm，满足对实际应用的要求。轻效率 将接近100％。这三个规格以前尚未满足。我们将设计一个 新颖的闭环驱动器电路具有良好的可靠性和高功率效率。另外，我们 将开发一个微型控制器，该微型控制器可以通过简单地按一个来改变焦点功率 按钮，这是实用且可靠的；在该项目的第二阶段，我们将开发一个 允许自动对焦功能的眼镜的原型。驾驶员的大小只会 5€2 mm3。将进行临床研究以评估佩戴者的运作方式和 感知新眼镜。 这种镜头承诺将成为常规区域部门的替代品 长老会使用的多焦点眼镜镜片。他们可能有潜力 彻底改变了长老会更正领域。新的眼镜将大大改善 人口的生活质量。应用程序可以扩展到varifocal的字段 操作电压低，直径相对较大的镜头元件和快速响应时间 是理想的。例如，此类镜头可以用作新的phoropter 测量折射率和视敏度，并在进行快速深度扫描 三维生物医学成像。用高品质光学器件校正低视力 外围也将产生很高的影响。这将是我们的下一个研究重点。