MOUSE MODEL FOR CYTOGENETIC DISORDERS

细胞遗传学疾病小鼠模型

• 批准号: 8550722
• 负责人: CATHLEEN LUTZ
• 金额: $ 65万
• 依托单位: JACKSON LABORATORY
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-09-23 至 2015-09-22
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8550722
• 关键词: Animal Model; Animal Testing; Breeding; Chromosomes, Human, Pair 10; Chromosomes, Human, Pair 16; Chromosomes, Human, Pair 17; Communities; Cytogenetics; Disease; Down Syndrome; Embryo; Freezing; Genetic; Germ Cells; Maine; Maintenance; Mouse Strains; Mus; National Institute of Child Health and Human Development; Procedures; Qualifying; Research; Research Personnel; Resources; Robertsonian Translocation; The Jackson Laboratory; Transgenic Mice; Trisomy; Writing; clinical phenotype; improved; mouse model; mutant; pathogen; programs; repository

To improve understanding of cytogenetic disorders, the NICHD provides ongoing support for a specialized respository that provides the scientific community with increasing numbers of mice with specific partial trisomies involving mouse chromosome 16, mouse chromosome 17, and mouse chromosome 10, specific Robertsonian translocation stocks, and, if appropriate specific mutant and transgenic mouse stocks relevant to Down syndrome research.

为了提高对细胞遗传疾病的理解，NICHD为专门的呼吸道提供了持续的支持，该呼吸道为科学界提供了越来越多的小鼠，其中涉及小鼠染色体16，小鼠染色体和小鼠染色体，第10个小鼠染色体，罗伯特森氏菌易位库存，以及特定的特定的转运库存，以及特定特定的突变型和转型小鼠库存相关的downs Syndrome consyndrome consyndrome consyndrome consyndrome consyndrome consyndorme conndrome consynds consymose越来越多。