Small Animal Imaging

小动物成像

• 批准号: 8302951
• 负责人: MATHEW laxman THAKUR
• 金额: $ 9.23万
• 依托单位: THOMAS JEFFERSON UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-06-01 至 2013-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8302951
• 关键词: Advisory Committees; Animal Housing; Animals; Cancer Center; Custom; Data; Funding; Generations; Guidelines; Image; Imaging Techniques; Internet; Investigation; Journals; Laboratory Animals; Magnetic Resonance Imaging; Malignant Neoplasms; Mission; Modality; Mus; Neurologic; Oryctolagus cuniculus; Peer Review; Photons; Physiology; Positron-Emission Tomography; Productivity; Protocols documentation; Publications; Radiology Specialty; Rattus; Research; Research Personnel; Resource Sharing; Resources; Services; Small Animal Imaging Shared Resource; Techniques; Training; Translational Research; Ultrasonography; Universities; Veterinarians; X-Ray Computed Tomography; anticancer research; in vivo; innovation; member; molecular imaging; oncology; optical imaging; pre-clinical; single photon emission computed tomography; tomography

SMALL ANIMAL IMAGING SHARED RESOURCE The Small Animal Imaging Shared Resource provides state-of-the-art in vivo molecular imaging capabilities to the investigators of the Kimmel Cancer Center. It was established under the direction of Dr. Mathew Thakur in April 2004 supported, to date, by the Thomas Jefferson University and the Department of Radiology. This resource provides non-invasive small animal imaging, with PET, SPECT, CT and ultrasound. These modalities offer innovative basic, as well as pre-clinical translational, research capabilities for studying patho-physiology and genesis of cancer. In addition to providing comprehensive imaging services the expertise exists to a) custom synthesize probes specific for targeted bio-markers; b) develop new image generation and analysis techniques; and c) train cancer investigators to harness the strengths of molecular imaging. The facility is supported by three AALAC accredited animal houses and two veterinarian staff members. Thus far this shared resource has supported fifteen federally funded investigations related to oncology and enhanced productivity as depicted by several publications in peer-reviewed journals.

小动物影像共享资源 小动物成像共享资源提供最先进的体内分子成像功能 给金梅尔癌症中心的研究人员。它是在Mathew博士的指导下成立的 Thakur 于 2004 年 4 月获得托马斯·杰斐逊大学和科学系的支持 放射学。该资源提供非侵入性小动物成像，包括 PET、SPECT、CT 和超声波。 这些模式提供了创新的基础以及临床前转化研究能力 癌症的病理生理学和发生。除了提供全面的影像服务外 现有专业知识 a) 针对目标生物标记物定制合成探针； b) 发展新形象 生成和分析技术； c) 培训癌症研究人员利用分子生物学的优势 成像。该设施由三个 AALAC 认可的动物饲养场和两名兽医人员提供支持 成员。到目前为止，这一共享资源已支持十五项联邦资助的调查 正如同行评审期刊上的几篇出版物所描述的那样，肿瘤学和生产力的提高。