MACROLIDES, STEROIDS, CYCLOPENTANOIDS, ETC SYNTHETIC DESIGNS

大环内酯类、类固醇类、环戊类化合物等合成设计

• 批准号: 7724152
• 负责人: BARRY M TROST
• 金额: $ 4.54万
• 依托单位: UNIVERSITY OF CALIFORNIA, SAN FRANCISCO
• 依托单位国家: 美国
• 财政年份: 2008
• 资助国家: 美国
• 起止时间: 2008-06-01 至 2009-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7724152
• 关键词: Antibodies; Antifungal Agents; Area; Biological; Cardiovascular system; Class; Computer Retrieval of Information on Scientific Projects Database; Funding; Grant; Inflammation; Institution; Macrolides; Research; Research Personnel; Resources; Source; Steroids; Therapeutic; United States National Institutes of Health; birth control; design; member; novel; programs

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Various compounds have broad biological effects. Thus, macolides are antibodies as well as antifungal agents. Steroids can be used in broad therapeutic areas, including birth control, inflammation, cardiovascular areas, etc. The program seeks to develop simple synthetic strategies to compound classes that have broad applications to make new and novel members, as well as known members, more readily available.

该子项目是利用该技术的众多研究子项目之一 资源由 NIH/NCRR 资助的中心拨款提供。子项目和 研究者 (PI) 可能已从 NIH 的另一个来源获得主要资金， 因此可以在其他 CRISP 条目中表示。列出的机构是 对于中心来说，它不一定是研究者的机构。 各种化合物具有广泛的生物效应。 因此，大环内酯类既是抗体又是抗真菌剂。 类固醇可用于广泛的治疗领域，包括节育、炎症、心血管领域等。该计划旨在开发简单的合成策略来合成具有广泛应用的类固醇，从而更容易地制造新的和新颖的成员以及已知的成员可用的。