Isolation of Liver Tissue RNA, Quality Assessment, and Arrays

肝组织 RNA 的分离、质量评估和芯片

• 批准号: 8535322
• 负责人: KELLY INMAN
• 金额: $ 14.34万
• 依托单位: INTEGRATED LABORATORY SYSTEMS, LLC
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-09-30 至 2013-09-29
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8535322
• 关键词: Dioxins; Evaluation; Female; Furans; Gene Expression; Hepatic; Liver; Mus; Oral Administration; RNA; Relative (related person); Tissues

This study will evaluate changes in hepatic gene expression in female B6C3F1 mice exposed to brominated and chlorinated dioxins or furans. Liver tissue from female B6C3F1 mice obtained from a NTP study entitled ¿Immunological Evaluation of the Relative Potency of a Single Oral Administration of Brominated and Chlorinated Dioxins and Furans in Female B6C3F1 Mice¿ was transferred to ILS

这项研究将评估暴露于溴化和氯化二恶英或Furans的雌性B6C3F1小鼠中肝素基因表达的变化。从NTP研究获得的雌性B6C3F1小鼠的肝组织，该研究的含有溴化和氯化二恶英的相对效力的免疫学评估雌性B6C3F1小鼠的相对效力已转移到ILS中。