TORS - Interdisciplinary Research Training Program, Project 8 of 10 TL1

TORS - 跨学科研究培训计划，项目 8（共 10 个）TL1

基本信息

批准号：
8292362
负责人：
JOYCE J REPA
金额：
$ 5.65万
依托单位：
UT SOUTHWESTERN MEDICAL CENTER
依托单位国家：
美国
项目类别：
财政年份：
2007
资助国家：
美国
起止时间：
2007-09-30 至 2012-06-30
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/8292362
关键词：
Address Admission activity Advertisements Advertising Animals Appointment Area Award Basic Science Behavioral Biochemistry Biomedical Research Cardiovascular Diseases Clinical Collaborations Committee Members Communication Comorbidity Core Facility Data Dedications Development Diabetes Mellitus Discipline Division of Basic Sciences Doctor of Medicine Doctor of Philosophy Education Educational Curriculum Educational Status Educational process of instructing Educational workshop Energy Metabolism Environment Ethics Evaluation Event Faculty Fellowship Funding Gastroenterology Genetic Goals Grant Health Hepatology Human Human Genetics Hypertension Image Individual Institution Instruction Interdisciplinary Study Internet Interview Journals Knowledge Laboratories Language Learning Legal patent Letters Literature Liver diseases Mentors Mentorship Metabolic Metabolic syndrome Metabolism Methods Molecular Molecular Biology Molecular Genetics National Research Service Awards Nature Neuroanatomy Neurobiology Notification Obesity Occupations Physiology Population Positioning Attribute Psychiatry Publications Qualifying Radiology Specialty Recommendation Recruitment Activity Regulation Research Research Activity Research Personnel Research Project Grants Research Training Review Committee Safety Services Societies Stroke Technical Expertise Techniques Technology Time Training Training Programs Underrepresented Minority Visit Woman Work bariatric surgery base career career development clinical epidemiology college design experience graduate student in vivo interest lectures medical schools meetings member mouse model non-alcoholic fatty liver nutrition peer post-doctoral training programs responsible research conduct symposium teacher

项目摘要

Obesity and its associated co-morbidities are major health problems in our society, contributing to diabetes mellitus, cardiovascular disease and stroke, hypertension, and non-alcoholic fatty liver disease. The objective of this postdoctoral training program is to provide a productive learning experience in biomedical research related to obesity. This application describes a comprehensive training program that takes advantage of a cadre of distinguished faculty mentors, a strong research environment endowed with technology core facilities, an extensive array of genetically defined mouse models and established human clinical populations, and a curriculum that allows educational opportunities to augment scientific knowledge, career development, and training in the responsible conduct of research. This program is unique in that a trainee will receive mentoring from two faculty members, each of a distinct scientific team , to promote the development and execution of an interdisciplinary research project to examine the behavioral, metabolic, and molecular events that cause obesity and the metabolic syndrome. This team-approach is supported by the collaborative environment of our 26 faculty members, drawn from 14 different Departments and Centers that have been organized into four teams to focus on The Central Regulation of Energy Metabolism (Team 1: Neuroanatomy, Neurobiology, Psychiatry), The Molecular Biology of Energy Metabolism (Team 2: Biochemistry, Molecular Genetics, Molecular Biology, and Physiology), In vivo Intermediary Metabolism (Team 3: Advanced Imaging, Human Nutrition, Hepatology/Gastroenterology), and Human Genetics and Energy Metabolism (Team 4: Bariatric Surgery, Clinical Epidemiology, and Genetics). Individuals accepted into this program will have a Ph.D., M.D./Ph.D., or M.D. degree and will have acquired some experience in one of many disciplines integral to this work prior to beginning their three-year fellowship. However, their training with two mentors, and work in two or more collaborative laboratory settings will allow them to become fluent in multiple, often disparate scientific languages (e.g. molecular biology, radiology, neuroanatomay,. nutrition, psychiatry, human genetics) thus permitting them to critically address unique scientific problems in an interdisciplinary manner. This program is designed, therefore, to train individuals who will become effective teachers and investigators capable of cutting-edge research in obesity.

肥胖及其相关的合并症是我们社会中的主要健康问题，导致糖尿病，心血管疾病和中风，高血压和非酒精性脂肪肝疾病。该博士后培训计划的目的是在与肥胖有关的生物医学研究中提供富有成效的学习经验。该应用程序描述了一项全面的培训计划，该计划利用了杰出的教师导师的干部，具有技术核心设施的强大研究环境，一系列广泛的遗传定义的老鼠模型和建立的人类临床人群，以及一项课程，允许教育机会增强科学知识，职业发展，职业发展和培训，以负责研究研究。该计划的独特之处在于，学员将获得来自两个教职员工的指导，即每个独特的科学团队，以促进跨学科研究项目的发展和执行，以研究导致肥胖和代谢综合征的行为，代谢和分子事件。我们的26名教职员工的协作环境支持了这一团队的要求，这些部门和中心从14个不同的部门和中心汲取了，这些部门和中心已组织成四个团队，专注于能量代谢的中心调节（团队1：神经解剖学，神经生物学，精神病学），能量生物学的分子生物学（生物学），生物学，分子，分子，分子，分子，分子生物学，分子，分子生物学，分子，分子，分子生物学。体内中介代谢（团队3：高级成像，人类营养，肝病学/胃肠病学）以及人类遗传学和能量代谢（团队4：减肥手术，临床流行病学和遗传学）。接受该计划的个人将获得博士学位，M.D./ph.d。或M.D.学位，并将在开始三年奖学金之前获得这项工作不可或缺的许多学科之一的经验。但是，他们与两位导师的培训，并在两个或多个协作实验室环境中工作将使他们能够流利，通常是不同的科学语言（例如，分子生物学，放射学，神经毒理学，营养，精神病学，人类，人类遗传学），从而使他们能够以一种互助的方式解决独特的科学问题。因此，该计划旨在培训将成为有效的教师和调查人员，能够在肥胖方面进行尖锐研究的个人。