Investigate the effect of mitochondrial energy state on Ca2+ sparks and handling

研究线粒体能量状态对 Ca2 火花和处理的影响

• 批准号: 8302507
• 负责人: Lufang Zhou
• 金额: $ 24.83万
• 依托单位: UNIVERSITY OF ALABAMA AT BIRMINGHAM
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-08-20 至 2014-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8302507
• 关键词: Acute; American; Calcium; Cardiac; Cardiac Myocytes; Cavia; Cells; Communication; Computer Simulation; Coupling; Development; Diagnostic; Disease; Electrophysiology (science); Energy Metabolism; Event; Feedback; Frequencies; Functional disorder; Glutathione; Heart Diseases; Heart failure; Image; Individual; Injury; Ion Channel; Ischemia; Knowledge; Lasers; Link; Membrane Potentials; Metabolic; Metabolism; Microscope; Mitochondria; Modeling; Molecular; NADH; Oxidation-Reduction; Oxidative Phosphorylation; Oxidative Stress; Pattern; Probability; Process; Production; Property; Pyrimidine Nucleotides; Reactive Oxygen Species; Regulation; Reperfusion Therapy; Rest; Ryanodine Receptor Calcium Release Channel; Ryanodine Receptors; Sarcomeres; Signal Transduction; Simulate; Site; Source; System; Therapeutic; Translating; Work; base; design; experimental analysis; follow-up; models and simulation; mortality; novel; spatiotemporal; sudden cardiac death; two-photon; uptake