HTS Core

高温超导核心

• 批准号: 7506380
• 负责人: James R Williamson
• 金额: $ 19.94万
• 依托单位: UNIVERSITY OF UTAH
• 依托单位国家: 美国
• 财政年份: 2007
• 资助国家: 美国
• 起止时间: 2007-08-27 至 2012-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7506380
• 关键词: Biochemical; Biological Assay; Biological Testing; Complex; Development; Goals; Laboratories; Molecular Bank; Screening procedure; Testing; United States National Institutes of Health; Validation; design; experience; high throughput screening; inhibitor/antagonist; member; programs

16) High Throughput Screening Development Core (Williamson. Director) Overview The goal of the High Throughput Screening (HTS) Development Core will be to adapt biochemical assays for complex formation developed by Center members into HTS inhibitor screens. The Williamson laboratory has facilities and experience in for design, testing, and validation of HTS assays. The ultimate goal will be to submit validated assays to screening programs, primarily the NIH Molecular Libraries and Screening Centers Network (MLSCN) for true high throughput screening. Hits emerging from these screens will be returned to the original Center members for biological testing.

16) 高通量筛选开发核心（Williamson。主任） 概述 高通量筛选 (HTS) 开发核心的目标是适应生化 中心成员开发的用于 HTS 抑制剂筛选的复合物形成测定法。这 Williamson 实验室拥有 HTS 检测设计、测试和验证的设施和经验。 最终目标是向筛选项目（主要是 NIH Molecular）提交经过验证的检测方法 图书馆和筛选中心网络 (MLSCN) 可实现真正的高通量筛选。热门歌曲不断涌现 这些屏幕将被送回原来的中心成员进行生物检测。