African Program for Research training in HIV, TB and associated opportunistic inf

非洲艾滋病毒、结核病和相关机会性感染研究培训计划

• 批准号: 7248032
• 负责人: David Allenberg Katzenstein
• 金额: $ 11.49万
• 依托单位: STANFORD UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2005
• 资助国家: 美国
• 起止时间: 2005-09-26 至 2010-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7248032
• 关键词: Africa South of the Sahara; African; Area; Basic Science; Biomedical Research; Caring; Clinical; Clinical Research; Clinical Trials; Collaborations; Development; Economics; Educational process of instructing; Epidemic; Epidemiology; Ethics; Faculty; HIV; Health Priorities; Health Sciences; Health system; Healthcare; Hepatitis B Virus; Hospitals; Human; Infant; Institutes; Internet; Laboratories; Laboratory Study; Life Expectancy; Literature; Mentors; Mycobacterium tuberculosis; Mycoses; Opportunistic Infections; Papillomavirus; Postdoctoral Fellow; Prevention; Prevention program; Reporting; Research; Research Methodology; Research Personnel; Research Project Grants; Research Training; Resources; Scientist; Simplexvirus; Students; Testing; Training; Translational Research; Tuberculosis; Universities; Zimbabwe; base; design; experience; improved; medical schools; programs; response; skills; tool; treatment program

The burden of HIV and opportunistic infections (Ol), particularly Mycobacterium tuberculosis (TB) are profoundly eroding infant survival, life expectancy, the economy and health care in Sub-Saharan Africa. Clinical, operational and translational research are recognized as essential responses to the epidemic. However, resource constraints, economic and health priorities limit capacity to train effective investigators and scientists. Research training and increased opportunities for researchers to develop internationally competitive skills are essential for effective responses to the HIV and TB epidemics. The proposed ICOHRTA collaboration between the Biomedical and Research Training Institute (BRTI), University of Zimbabwe (UZ) and Stanford University will provide clinical, laboratory, epidemiological, statistical and operational research training in an academic framework. The primary aim is to enable young African scientists to improve their research capacity: to design, implement and report on meaningful and relevant research. In collaboration with current clinical trials in HIV and TB prevention and treatment, the program will provide three critical areas of training: 1) Support and attachment of students to active clinical and laboratory research projects in Zimbabwe including field, laboratory, clinical, operational and health systems' delivery studies focused on prevention and treatment of HIV, TB, and Ol. 2) For post-graduate clinicians, a 2-year mentored clinical and laboratory experience in HIV, TB and opportunistic infections including Herpes simplex virus, human papilloma virus and hepatitis B virus and bacterial and fungal infection with opportunities for practical clinical experience in HIV clinical trials, prevention and care at Stanford University, and other US-medical schools and hospitals. 3) Training and experience in research for post-doctoral fellows from the US who will participate in the BRTI short-training courses as part of ongoing, substantial mentored clinical research with US and UZ faculty-investigators. To increase access to literature and developments in treatment and prevention, the program will develop, test and evaluate internet-based training and teaching tools to access interactive courses and training in good clinical practice, epidemiology, basic science, ethics, and translational research on the web. The aim is to equip students in the health sciences and young clinicians from Zimbabwe and the US to meet the challenges of these devastating epidemics through robust training in research methods and participation in clinical trials, operational and laboratory studies in Zimbabwe.

艾滋病毒和机会性感染 (Ol)，特别是结核分枝杆菌 (TB) 的负担正在严重损害撒哈拉以南非洲地区的婴儿存活率、预期寿命、经济和医疗保健。临床、操作和转化研究被认为是应对这一流行病的重要对策。然而，资源限制、经济和卫生优先事项限制了培训有效的研究人员和科学家的能力。研究培训和增加研究人员发展国际竞争力技能的机会对于有效应对艾滋病毒和结核病流行至关重要。生物医学和研究培训机构 (BRTI)、津巴布韦大学 (UZ) 和斯坦福大学之间拟议的 ICOHRTA 合作将在学术框架内提供临床、实验室、流行病学、统计和业务研究培训。主要目标是使年轻的非洲科学家能够提高他们的研究能力：设计、实施和报告有意义和相关的研究。与当前艾滋病毒和结核病预防和治疗方面的临床试验合作，该计划将提供三个关键的培训领域：1）支持和支持学生参与津巴布韦活跃的临床和实验室研究项目，包括现场、实验室、临床、操作和健康系统的交付研究侧重于艾滋病毒、结核病和流感的预防和治疗。 2) 对于研究生临床医生，具有 2 年 HIV、结核病和机会性感染（包括单纯疱疹病毒、人乳头瘤病毒和乙型肝炎病毒以及细菌和真菌感染）指导的临床和实验室经验，并有机会获得 HIV 临床的实际临床经验斯坦福大学以及其他美国医学院和医院的试验、预防和护理。 3) 为来自美国的博士后研究员提供研究培训和经验，他们将参加 BRTI 短期培训课程，作为与美国和乌兹别克斯坦研究人员进行的持续、实质性指导临床研究的一部分。为了增加获取文献和治疗和预防进展的机会，该计划将开发、测试和评估基于互联网的培训和教学工具，以获取良好临床实践、流行病学、基础科学、伦理学和转化研究方面的互动课程和培训。网络。其目的是让来自津巴布韦和美国的健康科学学生和年轻临床医生通过研究方法方面的强有力培训以及参与津巴布韦的临床试验、操作和实验室研究来应对这些毁灭性流行病的挑战。