Washington University Institute of Clinical and Translational Sciences (TL1)

华盛顿大学临床与转化科学研究所 (TL1)

基本信息

批准号：
7497171
负责人：
KENNETH S POLONSKY
金额：
$ 35.62万
依托单位：
WASHINGTON UNIVERSITY
依托单位国家：
美国
项目类别：
财政年份：
2007
资助国家：
美国
起止时间：
2007-09-17 至 2012-05-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/7497171
关键词：
Acquired Immunodeficiency Syndrome Address Administrator Admission activity Advertising Advisory Committees African American Agreement Alaska Native Alzheimer&apos s Disease Analysis of Variance Anatomy Animal Model Animals Anthropology Applications Grants Appointment Area Arts Asthma Attention Authorship Automobile Driving Award Barrier Contraception Basic Science Behavioral Behavioral Sciences Beneficence Biochemistry Bioethics Bioinformatics Biological Biological Markers Biology Biomedical Engineering Biomedical Research Biometry Bioterrorism Book Chapters Book Reviews Books Borocaptate Sodium Budgets California Cancer Center Candidate Disease Gene Cardiovascular system Case Study Case-Control Studies Cell Separation Chemicals Chi-Square Tests Chronic Disease Class Clinical Clinical Data Clinical Investigator Clinical Research Clinical Research Curriculum Award Clinical Sciences Clinical Trials Clinical Trials Design Code Cohort Studies Collaborations Collection Commit Communicable Diseases Communication Communities Community Health Community Practice Complement Complex Computer software Conduct Clinical Trials Confidentiality Conflict (Psychology)Conflict of Interest Contracts Critiques Data Data Analyses Data Collection Data Set Databases Development Diabetes Mellitus Diagnosis Diagnostic Discipline Discipline of Nursing Disclosure Disease Disease regression Doctor of Philosophy Documentation Drug usage Economics Education Educational Curriculum Educational Status Educational process of instructing Educational workshop Elements Employment End Point Engineering Engineering Psychology Enrollment Ensure Environment Environmental Health Environmental Risk Factor Epidemiologic Methods Epidemiology Ethical Issues Ethics Evaluation Evidence Based Medicine Evolution Exercise Experimental Designs Faculty Feedback Fellowship Program Female Fostering Funding Funding Agency Future Gender Gene Expression Generations Genetic Genomics Geographic Locations Goals Grant Guidelines Hand Head Healed Health Health Communication Health Information System Health Insurance Portability and Accountability Act Health Policy Health Promotion Health Sciences Health Services Health Services Research Health behavior Health education Health system Healthcare Hearing Heart failure Hereditary Disease Hispanics Home environment Hour Human Human Placental Lactogen Human Resources Human Subject Research Image Incubators Individual Industry Infectious Disease Epidemiology Inflammatory Informed Consent Institutes Institution Institutional National Research Service Award Instruction Intellectual Property Interdisciplinary Study International Internships Intervention Studies Joints Journals Knowledge Lead Leadership Learning Legal Letters Life Linear Models Link Literature Logistic Regressions Magnetic Resonance Imaging Mails Malaria Malignant Neoplasms Manuscripts Marketing Master of Science Master&apos s Degree Maternal and Child Health Maternity leave Mathematics Measurement Measures Medical Medical Ethics Medical Imaging Medical Students Medical center Medicine Mental Health Services Mentored Clinical Scientist Development Program Mentors Mentorship Metabolism Methodology Methods Minority Modeling Molecular Biology Molecular Profiling Monitor Morals Multimedia Names National Research Service Awards Native Americans Neuro-Oncological Ventral Antigen 2 Neurosciences Numbers Nurses Nursing Informatics Nursing Research Nursing Schools Observational Study Occupational Safety Occupational Therapy Occupational/Environmental Epidemiology Online Systems Operative Surgical Procedures Optical Methods Oral Organization and Administration Organizational Change Osteoporosis Otolaryngology Outcome Outcome Study Outcomes and Health Services Research Output Pamphlets Paper Participant Pathogenesis Pathology Patient Care Patient Recruitments Patients Pediatric Surgical Procedures Pediatrics Peer Review Performance Persons Pharmacogenetics Pharmacogenomics Pharmacy facility Phase Phenotype Physical therapy Physicians Physiology Pilot Projects Placebo Effect Policies Politics Population Genetics Population Heterogeneity Postdoctoral Fellow Pre-Eclampsia Preparation Prevention Principal Investigator Probability Procedures Process Productivity Program Development Program Evaluation Program Reviews Proteomics Protocols documentation Psychology Public Health Public Health Administration Public Health Nurses Public Health Nursing Public Health Schools Public Policy Publications Publishing Purpose Quality of life Questionnaire Designs Questionnaires ROC Curve Reading Recommendation Recording of previous events Records Recruitment Activity Regression Analysis Regulation Reporting Research Research Design Research Ethics Research Ethics Committees Research Methodology Research Personnel Research Project Grants Research Proposals Research Subjects Research Training Resources Rewards Rheumatoid Arthritis Risk Roentgen Rays Role Running SAS SECTM1 gene Safety Saints Sample Size Sampling San Francisco Schedule School Nursing Schools Science Science Policy Scientist Series Services Sickle Cell Anemia Side Social Interaction Social Responsibility Social Welfare Social Work Solutions Spectrum Analysis Statistical Methods Stream Structure Students Study Section Subjects Selections Suggestion Supervision Support of Research Surveys Survival Analysis Systemic Lupus Erythematosus Techniques Technology Testing Text Textbooks Therapeutic Intervention Thinking Time Tissues Toxicology Training Training Programs Training Support Training and Education Translational Research Translations Ultrasonics Underrepresented Minority United States National Academy of Sciences United States National Institutes of Health Universities Victoria Austrailia Vision Visit Walkers Washington Woman Women Physicians Women&apos s Health Work Workload Workplace Writing abstracting altretamine/cyclophosphamide/methotrexate protocol amsacrine/cyclophosphamide/hydroxyurea base bench to bedside biomedical informatics bone brain behavior career chronic leukemia clay clinical epidemiology college communication theory concept cyclopropapyrroloindole data management day design dissemination research editorial environmental toxicology essays expectation experience falls genetic epidemiology hazard healing health administration health care service organization health disparity human disease human subject improved innovation instrument interest lectures medical schools member minority trainee molecular pathology multidisciplinary novel nutrition patient oriented patient oriented research peer posters pre-doctoral professor programs radiotracer radius bone structure research and development research clinical testing research study response satisfaction skills social statistics success symposium theories tool trend user-friendly willingness

项目摘要

This CTSA application from Washington University in St. Louis (WU) is built on a long institutional history of outstanding biomedical research, research training, and patient care. WU is the recipient of the 4 clinical research and training grants that form the basis of the CTSA (GCRC, currently in its 46th year of funding, andK12, K30, and T32 grants.) Another critical element is WU's new BioMed 21 strategic initiative in multidisciplinary, collaborative research in genome sciences, biological imaging, and clinical investigation. All these elements will be conjoined with other existing resources at WU to form a transformational new Institute of Clinical and Translational Sciences (ICTS). By implementing the 15 key Program Functions described in this application, the ICTS will conceptually and operationally reinvent and reinvigorate clinical and translational research and clinical research training at WU. An unprecedented level of partnership with other academic, healthcare, community and scientific institutions that complement our core expertise in laboratory and clinical research and research training is central to the transformation that will be led by the ICTS. Our partners include BJC HealthCare, an integrated academic and community health care delivery system; Saint Louis University School of Public Health, Graduate School and Doisy College of Health Sciences; University of Missouri St. Louis College of Nursing; Southern Illinois University Edwardsville School of Nursing; and St. Louis College of Pharmacy; key organizations promoting community health as well as biomedical and pharmaceutical companies in the St. Louis area. The coupling of these resources creates an outstanding environment to make basic laboratory discoveries that can then be translated into clinical research protocols and ultimately into advances in clinical practice and patient care through extensive community interactions and commercial partnerships. To ensure the success of the ICTS, WU has made substantial commitments of space and financial support. Barnes-Jewish and St. Louis Children's Hospitals, our academic hospital partners, and BJCHeatthCare7Our affiliated health system, have also made substantial commitments to the clinical research activities of the ICTS. These additional resources coupled with the existing high quality programs in clinical and translational science ensure that WU will make outstanding contributions to this NIH initiative.

这份来自圣路易斯华盛顿大学的 CTSA 申请圣路易斯 (WU) 建立在杰出生物医学研究、研究培训、和病人护理。 WU 获得了 4 项临床研究和培训资助，这些资助构成了 CTSA（GCRC，目前已进入第 46 个资助年头，以及 K12、K30 和 T32 赠款。） element 是 WU 新的 BioMed 21 战略举措，涉及多学科、协作研究基因组科学、生物成像和临床研究。所有这些元素将结合在一起与西弗吉尼亚大学的其他现有资源一起组建一个变革性的新临床和临床研究所转化科学（ICTS）。通过实现本节中描述的 15 个关键程序功能应用程序，ICTS 将在概念上和操作上重塑并重振临床和西弗吉尼亚大学的转化研究和临床研究培训。与其他学术、医疗保健、社区和科学领域的伙伴关系达到前所未有的水平补充我们在实验室和临床研究以及研究培训方面的核心专业知识的机构是 ICTS 领导的转型的核心。我们的合作伙伴包括 BJC HealthCare、综合学术和社区卫生保健服务系统；圣路易斯大学学院公共卫生、研究生院和多伊西健康科学学院；密苏里大学圣路易斯分校护理学院；南伊利诺伊大学爱德华兹维尔护理学院；和圣路易斯学院药店;促进社区健康以及生物医学和制药的主要组织圣路易斯地区的公司。这些资源的耦合创造了优越的环境做出基本的实验室发现，然后将其转化为临床研究方案通过广泛的社区互动，最终推动临床实践和患者护理的进步和商业伙伴关系。为了确保ICTS的成功，WU做出了空间和财务方面的大量承诺支持。巴恩斯犹太医院和圣路易斯儿童医院是我们的学术医院合作伙伴，以及 BJCHeatthCare7我们所属的医疗系统，也对临床做出了实质性的承诺 ICTS 的研究活动。这些额外的资源加上现有的高质量临床和转化科学项目确保西弗吉尼亚大学将为此做出杰出贡献美国国立卫生研究院倡议。