ULTRASTRUCTURAL INVESTIGATION OF CYTONEMES AND THEIR CONTACT POINTS

细胞因子及其接触点的超微结构研究

• 批准号: 8169645
• 负责人: THOMAS B. KORNBERG
• 金额: $ 2.39万
• 依托单位: UNIVERSITY OF CALIFORNIA, SAN DIEGO
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-04-01 至 2011-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8169645
• 关键词: Cells; Computer Retrieval of Information on Scientific Projects Database; Development; Drosophila genus; Electron Microscopy; Funding; Grant; Growth Factor; Growth Factor Receptors; Institution; Investigation; Larva; Process; Research; Research Personnel; Resources; Signal Transduction; Source; United States National Institutes of Health; imaginal disc

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Cytonemes are long filopodial processes we believe are used in long range signaling of growth factors during development. Cytonemes express growth factor receptors and extend up to 800 um before contacting their target cells in the imaginal disk. We wish to use electron microscopy to study the contact points between cytonemes and target cells in Drosophila larvae.

该副本是利用众多研究子项目之一 由NIH/NCRR资助的中心赠款提供的资源。子弹和 调查员（PI）可能已经从其他NIH来源获得了主要资金， 因此，可以在其他清晰的条目中表示。列出的机构是 对于中心，这不一定是调查员的机构。 细胞质是我们认为在发育过程中生长因子的远距离信号中使用的长丝虫过程。 细胞表达生长因子受体，并延伸至800 um，然后在想象磁盘中接触其靶细胞。 我们希望使用电子显微镜研究果蝇幼虫中细胞质和靶细胞之间的接触点。