RASTER IMAGE CORRELATION SPECTROSCOPY (RICS) TRAINING

光栅图像相关光谱 (RICS) 培训

• 批准号: 8171001
• 负责人: Mark Jones
• 金额: $ 3.23万
• 依托单位: UNIVERSITY OF CALIFORNIA-IRVINE
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-08-01 至 2011-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8171001
• 关键词: Cell physiology; Cells; Computer Retrieval of Information on Scientific Projects Database; Fluorescence; Funding; Grant; Image; Institution; Laboratories; Life; Monitor; Nucleic Acids; Positioning Attribute; Property; RNA; Research; Research Personnel; Resources; Source; Spatial Distribution; Spectrum Analysis; Techniques; Therapeutic Effect; Training; United States National Institutes of Health; professor; programs

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Raster Image Correlation Spectroscopy: The Monitoring of RNA Quantification, Spatial Distribution and Diffusive Rates. A detailed understanding of RNA diffusive properties and spatial positioning within a live cell is yet to be acquired. The analysis program Raster Imaging Correlation Spectroscopy (Developed by Professor Enrico Gratton and Dr Michelle Digman, Laboratory for Fluorescence Dynamics) makes such an analysis feasible. A detailed understaning of nucleic acid dynamics would enhance the understanding of cellular processes as well as enable the application of the developed analysis technique to identify the effects of therapeutic treatments on single live cells.

该子项目是利用该技术的众多研究子项目之一 资源由 NIH/NCRR 资助的中心拨款提供。子项目及 研究者 (PI) 可能已从 NIH 的另一个来源获得主要资金， 因此可以在其他 CRISP 条目中表示。列出的机构是 对于中心来说，它不一定是研究者的机构。 光栅图像相关光谱：RNA 定量、空间分布和扩散率的监测。 目前尚未详细了解活细胞内 RNA 扩散特性和空间定位。分析程序光栅成像相关光谱（由荧光动力学实验室的 Enrico Gratton 教授和 Michelle Digman 博士开发）使这种分析变得可行。对核酸动力学的详细了解将增强对细胞过程的理解，并能够应用已开发的分析技术来确定治疗对单个活细胞的影响。