INGTEGRATING BIOMATERIALS & BIOPHOTONICS TO ASSESS ECM MECHANICS

整合生物材料

• 批准号: 8170961
• 负责人: Elliot Lawrence Botvinick
• 金额: $ 1.49万
• 依托单位: UNIVERSITY OF CALIFORNIA-IRVINE
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-08-01 至 2011-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8170961
• 关键词: Biocompatible Materials; Biophotonics; Cells; Computer Retrieval of Information on Scientific Projects Database; Computer software; Engineering; Environment; Extracellular Matrix; Fiber; Funding; Goals; Grant; Institution; Mechanics; Research; Research Personnel; Resources; Source; Time; Tissues; United States National Institutes of Health

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The major goals of this project are to correlate bulk tissue mechanics with local micro-environment mechanics in engineered ECM tissues. specific use at LFD - Use of reflection confocal and SIM-FCS software to look at correlations along and between fibers, as well as matrix deformation by cells over time.

该子项目是利用该技术的众多研究子项目之一 资源由 NIH/NCRR 资助的中心拨款提供。子项目及 研究者 (PI) 可能已从 NIH 的另一个来源获得主要资金， 因此可以在其他 CRISP 条目中表示。列出的机构是 对于中心来说，它不一定是研究者的机构。 该项目的主要目标是将工程 ECM 组织中的体组织力学与局部微环境力学联系起来。 LFD 的具体用途 - 使用反射共焦和 SIM-FCS 软件来查看纤维沿线和纤维之间的相关性，以及细胞随时间的矩阵变形。