CARDIAC TROPONIN- T: A SPECIFIC BIOCHEMICAL MARKER OF MYOCARDIAL DYSFUNCTION, MO

心肌肌钙蛋白-T：心肌功能障碍的特定生化标志物，MO

• 批准号: 8174521
• 负责人: VIRENDER K REHAN
• 金额: $ 1.06万
• 依托单位: LUNDQUIST INSTITUTE FOR BIOMEDICAL INNOVATION AT HARBOR-UCLA MEDICAL CENTER
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-12-01 至 2010-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8174521
• 关键词: Adult; Age-Months; Biochemical Markers; Birth; Blood Tests; Cardiac; Computer Retrieval of Information on Scientific Projects Database; Enrollment; Fetal Weight; Funding; Grant; Heart; Hospitals; Infant; Informed Consent; Institution; Measurement; Monitor; Mothers; Myocardial dysfunction; Outcome; Pregnant Women; Research; Research Personnel; Resources; Source; Testing; Time; Troponin; United States National Institutes of Health; Very Low Birth Weight Infant; heart function; heart imaging

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The purpose of this study is to establish whether heart function in very low birth weight infants can be predicted by a simple blood test and whether this serial measurements of this test can predict overall outcome in very low birth infants .This blood test has been done in adults to detect damage in adults. It is hoped that this test will allow us to detect heart damage in very low birth infants earlier and provide us with more details on their long term outcome. This study will help us in better understanding of the heart function in very low birth weight infants and may provide a reliable blood test to not only monitor heart function but also to predict the ultimate outcome in very low birth weight infants. The babies enrolled will be lesser than 1500 gm. Pregnant women admitted to the hospital who have an estimated fetal weight <1500 g will be approached for informed consent for enrollment prior to delivery. If we are unable to approach mother prior to delivery, she will be approached after the delivery for enrollment. They will have special heart scans to look at their heart four times during the first week (Days 1,2,3, and 7 after delivery and at 1 month of age). Heart scans are routinely performed to detect heart problems in NICUs, and majority of very low birth infants have multiple heart scans performed during their stay in the NICU.

该副本是利用众多研究子项目之一 由NIH/NCRR资助的中心赠款提供的资源。子弹和 调查员（PI）可能已经从其他NIH来源获得了主要资金， 因此，可以在其他清晰的条目中表示。列出的机构是 对于中心，这不一定是调查员的机构。 这项研究的目的是确定通过简单的血液检查能够预测出非常低出生体重的婴儿的心脏功能以及该测试的这种连续测量是否可以预测非常低的出生婴儿的总体结果。成人检测成人损害。希望这项测试能够使我们能够早期发现非常低的出生婴儿的心脏损伤，并为我们提供有关其长期结果的更多细节。这项研究将帮助我们更好地理解非常低的出生体重婴儿的心脏功能，并可能提供可靠的血液检查，不仅可以监测心脏功能，还可以预测非常低的出生体重婴儿的最终结果。 入学的婴儿将少于1500克。孕妇允许在分娩前接受估计胎儿体重估计<1500 g的胎儿体重<1500 g的孕妇。如果我们在分娩前无法接近母亲，则将在交货后与她接触。他们将进行特殊的心脏扫描，在第一周（第1,2,3天，分娩后7个月和1个月大）四次看自己的心脏。常规进行心脏扫描以检测NICUS的心脏问题，大多数非常低的出生婴儿在NICU逗留期间进行了多次心脏扫描。