PREPARATORY INTERVENTIONS FOR LIFE AFTER BREAST CANCER

乳腺癌术后生活的准备性干预措施

• 批准号: 8120897
• 负责人: Annette L Stanton
• 金额: $ 12.48万
• 依托单位: UNIVERSITY OF COLORADO DENVER
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/8120897
• 关键词: Address; Adverse effects; Age; Biostatistics Core; Breast Cancer Treatment; CD-ROM; Callback; Cancer Information Service; Cancer Patient; Caring; Clinical; Cognitive; Collaborations; Computer software; Computers; Control Groups; Coping Skills; Data; Development; Distress; Dose; Education; Educational Intervention; Effectiveness of Interventions; Enrollment; Ethnic Origin; Glean; Goals; Health; Health Services Research; High Risk Woman; Informal Social Control; Information Specialists; Internet; Intervention; Life; Malignant Neoplasms; Measurement; Mediating; Mediation; Mediator of activation protein; Medical; Mental Health; Mission; Modeling; Monitor; Multimedia; Outcome; Participant; Patients; Phase; Printing; Process; Protocols documentation; Quality Control; Race; Randomized; Recommendation; Recording of previous events; Records; Recruitment Activity; Regional Cancer; Relative (related person); Reporting; Research; Risk; Science; Self Efficacy; Services; Speed; Stress and Coping; Survivors; System; Telephone; Telephone Interviews; Testing; Thinking; Time; Treatment Efficacy; United States; Visual Aid; Woman; base; cancer recurrence; chemotherapy; coping; cost; design; effective intervention; efficacy testing; follow-up; high risk; information processing; innovation; intervention effect; malignant breast neoplasm; peer; physical conditioning; primary outcome; programs; response; secondary outcome; service intervention; skills; social; survivorship; theories; therapy development; virtual

REPARATORY INTERVENTIONS FOR LIFE AFTER BREAST CANCER - Project 3 In the United States, over 2 million women live with a history of breast cancer. The re-entry transition from cancer patient to survivor is an understudied and challenging period. Using a theory-driven conceptual framework, Project 3 of this Cancer Information Service Research Consortium (CISRC) proposal involves development and testing of interventions to promote informed re-entry to life after breast cancer treatment. The six primary aims are to: (1) develop and test a highly innovative multimedia educational intervention'(CD-ROM, Internet), the Virtual Cancer Information Service (V-CIS); (2) develop and test a telephone callback protocol conducted by the NCI's Cancer Information Service (CIS) Information Specialists; (3) evaluate these interventions in randomized, 3-group stepped and 2-group designs, which, for those with computer access, (a) Group 1=a control group] receiving standard CIS service and print material (NCI's Facing Forward and What You Need To Know about Breast Cancer); (b) Group 2=standard care + V-CIS; (c) Group 3=standard care + V-CIS + two CIS telephone callbacks; and, for those who lack computer access, (d) Group 1 A=control=same standard print as Group 1; (e) Group 2A=standard print * 2 CIS intervention callbacks; (4) evaluate a theory-driven test of mediators (i.e., self-efficacy, perceived coping skill) of intervention effects; (5) test putative moderators (e.g., participant age) of intervention effects; (6) with the CIS, plan dissemination. To test the efficacy of the intervention, 1,800 breast cancer callers to the CIS will be enrolled, and depending on computer access, randomized to the 3-group or the 2-group design, and followed at 2, 6, and 12 months post-baseline. Conforming to a dose-response gradient, the primary hypothesis is that Group 3 > Group 2 > Group i1 (and Group 2A > Group 1 A) with regard to positive outcomes in the domains of psychological health, physical health, interpersonal functioning, and life perspectives. Hypotheses regarding how (i.e., mediators) and for whom (i.e., moderators) the interventions are effective also will be examined. Project 3 is unique in that it examines a state-of-the-science software program and proactive CIS-initiated telephone callbacks, thus addressing the primary service mission of the CIS. Contingent upon findings, the goal of the CISRC is to prepare the intervention for dissemination within the CIS, as well as other service programs nationwide.

乳腺癌术后生活的修复干预措施 - 项目 3 在美国，超过 200 万女性有乳腺癌病史。癌症患者的再入境转变 对于幸存者来说，这是一个未被充分研究且充满挑战的时期。使用理论驱动的概念框架，本项目的项目 3 癌症信息服务研究联盟 (CISRC) 提案涉及干预措施的开发和测试 促进乳腺癌治疗后知情地重返生活。六个主要目标是：（1）开发和测试高度 创新的多媒体教育干预（CD-ROM、互联网）、虚拟癌症信息服务（V-CIS）； (2) 开发并测试由 NCI 癌症信息服务 (CIS) 执行的电话回拨协议 专家； (3) 以随机、3 组阶梯式和 2 组设计评估这些干预措施，对于那些患有 计算机访问，(a) 第 1 组 = 对照组] 接收标准 CIS 服务和打印材料（NCI 的“面向前” 以及您需要了解的有关乳腺癌的信息）； (b) 第 2 组 = 标准护理 + V-CIS； (c) 第 3 组 = 标准护理 + V-CIS+2个CIS电话回拨；对于那些无法使用计算机的人，(d) 第 1 组 A=控制=相同标准 作为第 1 组打印； (e) 第 2A 组=标准打印 * 2 个 CIS 干预回调； (4) 评估理论驱动的测试 干预效果的中介因素（即自我效能、感知的应对技巧）； (5) 测试假定的主持人（例如参与者 干预效果的年龄）； (6)配合CIS，策划传播。为了测试干预措施的效果，研究人员对 1,800 名乳房进行了研究 CIS 的癌症呼叫者将被登记，并根据计算机访问情况，随机分为 3 组或 2 组 设计，并在基线后 2、6 和 12 个月进行随访。符合剂量反应梯度，主要 假设是第 3 组 > 第 2 组 > 第 i1 组（以及第 2A 组 > 第 1 A 组） 心理健康、身体健康、人际关系功能和生活观点等领域。关于的假设 干预措施如何（即调解员）以及对谁（即调解员）有效也将受到审查。项目3是 其独特之处在于它检查了最先进的软件程序和主动 CIS 发起的电话回叫，因此 解决 CIS 的主要服务使命。根据调查结果，CISRC 的目标是准备 独联体内部的传播干预以及全国范围内的其他服务计划。