MOLECULAR BIOLOGY AND BIOCHEMISTRY CORE

分子生物学和生物化学核心

• 批准号: 8148036
• 负责人: Kathryn L Sandberg
• 金额: $ 19.81万
• 依托单位: GEORGETOWN UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-04-01 至 2012-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8148036
• 关键词: Abetalipoproteinemia; Address; Adenoviruses; Animal Model; Animals; Apolipoproteins B; Arts; Autopsy; Bar Codes; Biochemistry; Capsid; Chronic; Clinical; Clinical Research; Complementary DNA; Computational Biology; DNA; Data; Disease model; Dyslipidemias; Evaluation; Familial Hypercholesterolemia; Family; Frequencies; Gene Transfer; Genetic; Genetic Recombination; Genome; Goals; Grant; Hepatocyte; Hereditary Disease; Infection; Inflammation; Liver; Liver neoplasms; Macaca; Macaca mulatta; Measures; Mediating; Metabolism; Modeling; Molecular; Molecular Biology; Mus; Oncogenic; Organ; Oryctolagus cuniculus; Outcome; Phase; Population; Prevalence; Primates; Proteins; Recombinants; Relative (related person); Research Design; Risk; Safety; Serotyping; Site; Source; Steatohepatitis; Techniques; Testing; Tissues; Toxic effect; Transgenes; Transportation; Triglycerides; Tropism; Tumorigenicity; adeno-associated viral vector; base; gene therapy; genome-wide; in vivo; monomer; mouse model; nonhuman primate; novel; pre-clinical; therapeutic transgene; treatment strategy; tumorigenesis; vector; vector genome