EVALUATION OF CONNECTIONS A NEW HIV PREVENTION INTERVENTION FOR BLACK MSM/W

联系评估 针对黑人 MSM/W 的新 HIV 预防干预措施

• 批准号: 7563431
• 负责人: JENNIFER L LAUBY
• 金额: $ 24.67万
• 依托单位: PUBLIC HEALTH MANAGEMENT CORPORATION
• 依托单位国家: 美国
• 财政年份: 2008
• 资助国家: 美国
• 起止时间: 2008-09-30 至 2012-09-29
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7563431
• 关键词: EVALUATION; CONNECTIONS; NEW; HIV; PREVENTION

Description (provided by applicant): Black men who have sex with men (MSM) have the highest rates of HIV infection in the United States and represent a population in need of new HIV prevention interventions. Although 20 to 40% of Black MSM are estimated to have female partners, no interventions tailored to the needs of Black MSM/W have been developed and rigorously evaluated. Philadelphia Health Management Corporation proposes to develop, implement, and evaluate an individual-level intervention (ILI), titled "Connections", that will assist Black MSM/W to reduce their risk for acquiring and transmitting HIV infection. This intervention will address the effect of individual level factors, interpersonal relationships including sexual, peer and family relationships, and sociocultural influences on the sexual risk behaviors of MSM/W. The intervention will consist of six counseling sessions held between a social worker (intervention specialist) and participant, and will be guided by three theoretical perspectives: an ecological perspective of behavior, stress and coping theory, and social cognitive theory. The COLOURS Organization, the sole agency in Philadelphia dedicated to exclusively serving the Black LGBT community, will be a key collaborator in the development and implementation of the intervention. The evaluation design utilizes a randomized controlled trial to test the effectiveness of the proposed intervention. Respondent Driven Sampling (RDS) will be used to recruit 250 HIV-positive and HIV-negative Black bisexuallyactive men into this study. The specific aims of this research are to: 1. develop a new theoretically-based individual-level HIV prevention intervention culturally tailored to the needs of HIV-positive and HIV-negative Black MSM/W; 2. evaluate the intervention with a randomized control group design, using RDS to recruit 250 Black MSM/W who do not inject drugs and who report recent unprotected sex; 3. assess the efficacy of the intervention and test the intervention model through the collection of behavioral risk assessments and HIV and STD testing at three time points: baseline, immediately post-intervention and three-months post-intervention; 4. examine and describe individual factors, interpersonal relationships and network factors, and socio-cultura factors that may affect risk behaviors for HIV infection and transmission among Black MSM/W; and, 5. develop recommendations for recruiting Black bisexually-active men and providing them with targeted HIV prevention interventions. Evaluation data collection will be conducted using ACASI. Data analysis will include Repeated Measures ANOVA to make assessments of changes over time and intervention dose effects and structural equation modeling to assess causal associations between factors in the conceptual model. This proposed study has significance for increasing our understanding various types of factors that may affect sexual risk behaviors of Black MSM/W as well as potentially providing an important new tool for HIV prevention specifically targeting the needs and risk behaviors of Black MSM/W.

描述（由申请人提供）：在美国，男男性行为者 (MSM) 的黑人艾滋病毒感染率最高，他们是需要新的艾滋病毒预防干预措施的人群。尽管据估计 20% 至 40% 的黑人 MSM 有女性伴侣，但尚未制定并严格评估针对黑人 MSM/W 需求的干预措施。费城健康管理公司提议制定、实施和评估一项名为“连接”的个人层面干预措施 (ILI)，该干预措施将帮助黑人 MSM/W 降低感染和传播 HIV 感染的风险。该干预措施将解决个人层面因素、人际关系（包括性关系、同伴关系和家庭关系）以及社会文化对 MSM/W 性危险行为的影响。干预将包括在社会工作者（干预专家）和参与者之间举行的六次咨询会议，并将以三种理论观点为指导：行为的生态观点、压力和应对理论以及社会认知理论。 COLORS 组织是费城唯一一家专门为黑人 LGBT 群体提供服务的机构，它将成为制定和实施干预措施的关键合作者。评估设计利用随机对照试验来测试所提出的干预措施的有效性。受访者驱动抽样 (RDS) 将用于招募 250 名 HIV 阳性和 HIV 阴性的黑人双性恋男性参与本研究。本研究的具体目标是： 1. 开发一种新的基于理论的个人层面艾滋病毒预防干预措施，该干预措施在文化上适合艾滋病毒阳性和艾滋病毒阴性黑人 MSM/W 的需求； 2. 采用随机对照组设计评估干预措施，使用 RDS 招募 250 名不注射毒品且报告近期有无保护性行为的黑人 MSM/W； 3. 通过在基线、干预后立即和干预后三个月三个时间点收集行为风险评估和 HIV 和 STD 检测来评估干预效果并测试干预模型； 4. 检查和描述可能影响黑人 MSM/W 中 HIV 感染和传播危险行为的个人因素、人际关系和网络因素以及社会文化因素； 5. 制定招募活跃双性恋黑人男性并向他们提供有针对性的艾滋病毒预防干预措施的建议。评估数据收集将使用 ACASI 进行。数据分析将包括重复测量方差分析，以评估随时间的变化和干预剂量效应，以及结构方程模型，以评估概念模型中因素之间的因果关系。这项拟议的研究对于增加我们对可能影响黑人 MSM/W 性危险行为的各种因素的了解具有重要意义，并有可能为专门针对黑人 MSM/W 的需求和危险行为的艾滋病毒预防提供重要的新工具。