Addressing Young Men's Substance Use and HIV Risk

解决年轻男性的药物滥用和艾滋病毒风险

• 批准号: 7005858
• 负责人: JENNIFER L LAUBY
• 金额: $ 49.15万
• 依托单位: PUBLIC HEALTH MANAGEMENT CORPORATION
• 依托单位国家: 美国
• 财政年份: 2005
• 资助国家: 美国
• 起止时间: 2005-09-10 至 2011-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7005858
• 关键词: AIDS education /prevention; African; African American; African Caribbean; HIV infections; adolescence (12-20); alcoholism /alcohol abuse; behavioral /social science research tag; caucasian American; clinical research; education evaluation /planning; epidemiology; geographic difference; health behavior; high risk behavior /lifestyle; homosexuals; human subject; longitudinal human study; male; mass information media; peer group; racial /ethnic difference; sex behavior; social support network; socioeconomics; substance abuse related behavior; substance abuse related disorder; young adult human (21-34)

DESCRIPTION (provided by applicant): Young men who have sex with men (YMSM) have unique needs for targeted and tailored HIV prevention messages. HIV infection rates among MSM remain high, particularly among men under the age of 30 and for Black YMSM, whose HIV infection rates are over four times those of White YMSM. The use of drugs and alcohol has been linked to increased sexual risk for HIV among MSM yet no intervention addressing substance use and sexual risk within this population has been rigorously evaluated. Philadelphia Health Management Corporation (PHMC) proposes to develop, implement, and evaluate a community-level intervention for Black and White substance-using MSM between the ages of 15 and 29. The intervention, implemented with the collaboration of a community service organization, the Mazzoni Center, will be designed to change both social norms and risk behavior using persuasive media communication and interpersonal networking as primary intervention strategies. The proposed project aims to: 1) examine patterns and contexts of episodic substance use among YMSM; 2)compare patterns of substance use for Black and White YMSM, and differences by age, sexual identity and socio-economic status; 3) clarify the association between patterns and contexts of substance use and sexual risk behaviors; 4) evaluate the efficacy of a community-level intervention for substance-using YMSM to decrease sexual risk for HIV, through strengthening social norms, increasing perceived risk, and enhancing self-efficacy and positive attitudes to HIV prevention; 5) measure the differential impact of intervention messages on sexual risk behavior for subgroups of YMSM; 6) determine if a reduction in substance use leads to a decrease in sexual risk behaviors. During the formative research phase, qualitative data will be obtained through focus groups and in-depth interviews to refine the conceptual model and the media materials. The intervention evaluation will collect quantitative data from YMSM in both Philadelphia PA and the comparison community of Baltimore MD, using geocoding and census tract data to control for demographic and socio-economic differences. A Solomon four-group design will be used to collect data from panel and cross-sectional samples in intervention and comparison communities. Four annual waves of interviews (baseline, 12, 24, and 36 months) will enable us to examine exposure to the intervention, changes in norms and behavior, and long-term intervention effects. A total of 650 men will be interviewed in Philadelphia and 400 in Baltimore. The data will be analyzed using multivariate techniques, including generalized linear model (GLM) repeated measures analysis and cumulative logit models. The study results will provide needed information on substance use and sexual risk of Black and White YMSM and have direct implications for implementing effective interventions to this high-risk population.

描述（由申请人提供）：男男性行为者 (YMSM) 对有针对性和量身定制的艾滋病毒预防信息有着独特的需求。 MSM 中的 HIV 感染率仍然很高，尤其是 30 岁以下男性和黑人 YMSM，其 HIV 感染率是白人 YMSM 的四倍多。吸毒和酗酒与 MSM 中感染艾滋病毒的性风险增加有关，但尚未对解决该人群中的药物使用和性风险的干预措施进行严格评估。费城健康管理公司 (PHMC) 提议针对 15 至 29 岁之间使用药物的黑人和白人 MSM 制定、实施和评估社区级干预措施。该干预措施是与社区服务组织、马佐尼中心旨在利用说服性媒体传播和人际网络作为主要干预策略来改变社会规范和风险行为。 拟议项目的目的是： 1) 检查 YMSM 中间歇性物质使用的模式和背景； 2）比较黑人和白人YMSM的物质使用模式，以及年龄、性别认同和社会经济地位的差异； 3）阐明物质使用模式和背景与危险性行为之间的关联； 4) 通过加强社会规范、增加感知风险、提高自我效能和对艾滋病毒预防的积极态度，评估针对物质使用 YMSM 的社区一级干预措施的有效性，以降低感染艾滋病毒的性风险； 5) 衡量干预信息对 YMSM 亚组性危险行为的不同影响； 6) 确定物质使用的减少是否会导致危险性行为的减少。 在形成性研究阶段，将通过焦点小组和深入访谈获得定性数据，以完善概念模型和媒体材料。干预评估将从宾夕法尼亚州费城的 YMSM 和马里兰州巴尔的摩的比较社区收集定量数据，使用地理编码和人口普查区数据来控制人口和社会经济差异。将使用所罗门四组设计从干预和比较社区的面板和横截面样本中收集数据。每年四波访谈（基线、12、24 和 36 个月）将使我们能够检查干预措施的暴露程度、规范和行为的变化以及长期干预效果。费城将总共采访 650 名男性，巴尔的摩将采访 400 名男性。将使用多元技术对数据进行分析，包括广义线性模型 (GLM) 重复测量分析和累积 Logit 模型。研究结果将提供有关黑人和白人 YMSM 的物质使用和性风险的必要信息，并对针对这一高危人群实施有效干预措施产生直接影响。