CTSA INFRASTRUCTURE FOR PEDIATRIC RESEARCH

CTSA 儿科研究基础设施

• 批准号: 8366082
• 负责人: Julian Solway
• 金额: $ 102.9万
• 依托单位: UNIVERSITY OF CHICAGO
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-06-01 至 2012-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8366082
• 关键词: Chicago; Pediatric Research; Research Infrastructure; Translational Research; Universities

This subproject represents an estimate of the percentage of the CTSA funding that is being utilized for a broad area of research (AIDS research, pediatric research, or clinical trials). The Total Cost listed is only an estimate of the amount of CTSA infrastructure going towards this area of research, not direct funding provided by the NCRR grant to the subproject or subproject staff. The ultimate goals of the University of Chicago CTSA program are to train scientists and health care providers at the University, our partner institutions, and our Community to determine the molecular underpinnings of disease or disease predisposition in any individual patient; to develop, test, implement, and make readily available to residents in our Community personalized therapies directed toward those individual underpinnings; and to do this in a way that is rigorous, valid, efficient, ethical, and respectful of our Community's needs and values. In a robust alliance with Argonne National Laboratory, the Illinois Institute of Technology, and two large healthcare organizations, we will undertake three bold new steps that will transform clinical and translational research at our institutions and in our Community: 1) Creation of an Institute for Translational Medicine, a new University-wide structure to collect, integrate, and disseminate the intellectual, organizational, and resource infrastructure needed to promote and support multidisciplinary translational research collaborations; 2) Synergistic research interaction with a new UC Urban Health Initiative which, through partnership with Community stakeholders, aims to improve Community health care access and quality, to build health literacy and trust throughout the Community, to enhance a translational research program informed by and responsive to the needs of the Community, and so to reduce health disparities; and 3) Establishment of a new academic Committee on Clinical and Translational Science and of multiple novel training programs to encourage and develop careers in clinical and translational research, intended for high school students through university faculty and across the entire translational research spectrum. Our consortium of dedicated CTSA investigators will employ a systems medicine approach to leverage their particular expertise in social science, genetic medicine, and integrative therapeutics. Together, this team and these transforming innovations will allow the University of Chicago CTSA to prepare the next generation of clinical and translational researchers to realize our vision of widely available, effective, and personalized therapies that find everyday application in Community practice and thereby reduce health disparities in diverse adult and pediatric populations.

该子项目代表CTSA资金百分比的估计值 被用于广泛的研究领域（艾滋病研究，儿科研究或 临床试验）。 列出的总成本只是CTSA数量的估计值 基础设施朝向这一研究领域，而不是直接提供的资金 NCRR授予subproject或subproject人员。 芝加哥大学CTSA计划的最终目标是培训大学，我们的合作伙伴机构和我们的社区的科学家和医疗保健提供者，以确定任何个体患者的疾病或疾病易感性的分子基础；开发，测试，实施和使我们的社区个性化疗法中的居民适应针对那些个人基础的疗法；并以严格，有效，高效，道德和对社区的需求和价值观的尊重的方式来做到这一点。 In a robust alliance with Argonne National Laboratory, the Illinois Institute of Technology, and two large healthcare organizations, we will undertake three bold new steps that will tr​​ansform clinical and translational research at our institutions and in our Community: 1) Creation of an Institute for Translational Medicine, a new University-wide structure to collect, integrate, and disseminate the intellectual, organizational, and resource infrastructure needed to promote and support multidisciplinary translational research合作； 2）与新的UC城市健康计划的协同研究互动，该计划通过与社区利益相关者的合作伙伴关系，旨在改善社区保健访问和质量，在整个社区中建立健康素养和信任，以增强由社区需求所告知和响应的翻译研究计划，从而减少健康偏见； 3）成立了一个新的临床和转化科学学术委员会以及多种新颖的培训计划，以鼓励和发展临床和翻译研究的职业，该研究旨在通过大学教师以及整个翻译研究范围为高中生提供。我们由专门的CTSA研究人员组成的联盟将采用系统医学方法来利用其在社会科学，遗传医学和综合治疗方面的特殊专业知识。这支团队和这些转型创新将使芝加哥大学CTSA能够为下一代临床和转化研究人员做好准备，以实现我们对广泛可用，有效和个性化疗法的愿景，这些疗法在社区实践中发现日常应用，从而减少成人和儿科种群的健康差异。