DNA Demethylation and Transcriptional Gene Silencing

DNA 去甲基化和转录基因沉默

• 批准号: 8217130
• 负责人: JIAN-KANG ZHU
• 金额: $ 32.82万
• 依托单位: PURDUE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2004
• 资助国家: 美国
• 起止时间: 2004-05-01 至 2012-07-22
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8217130
• 关键词: Adenosine; Animal Model; Base Excision Repairs; Biochemical; Chromatin Structure; Complex; DNA; DNA Methylation; DNA glycosylase; Data; Development; Disease; Environment; Enzymes; Epigenetic Process; Functional RNA; Gene Expression Regulation; Gene Silencing; Gene Targeting; Genes; Genetic; Genetic Transcription; Genome; Genome Stability; Genomic Imprinting; Genomics; Goals; Histones; Homologous Gene; Hypermethylation; Investigation; Lyase; Malignant Neoplasms; Methylation; Methyltransferase; Modification; Mouse-ear Cress; Mutate; Nucleic Acids; Pathway interactions; Pattern; Phosphotransferases; Physiological; Play; Property; Proteins; RNA; RNA Binding; RNA-Binding Proteins; ROS1 gene; Reaction; Regulation; Role; Small Interfering RNA; Small RNA; Sulfur; Sulfur Metabolism Pathway; System; Testing; Transgenes; Variant; demethylation; genome-wide; histone modification; in vivo; mutant; prevent; promoter