Short-Term Training to Increase the Diversity Pipeline in Heart/Lung/Blood Resear

短期培训以增加心/肺/血液研究的多样性管道

基本信息

批准号：
8154947
负责人：
MARLYS Hearst WITTE
金额：
$ 23.69万
依托单位：
UNIVERSITY OF ARIZONA
依托单位国家：
美国
项目类别：
财政年份：
2011
资助国家：
美国
起止时间：
2011-06-01 至 2016-05-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/8154947
关键词：
Area Arizona Attitude Basic Science Biocompatible Materials Bioinformatics Biology Biomedical Engineering Biomedical Research Blood Brain Cardiovascular system Clinical Clinical Research Clinical Sciences Clinical Trials Communication Communities Complex Computer Simulation Curiosities Databases Development Development Plans Disadvantaged Educational Curriculum Educational workshop Effectiveness Equilibrium Esapent Evaluation Faculty Fostering Future Genomics Goals Health Health Professional Heart Heart Diseases Hematological Disease Hematopoietic Neoplasms Hypertrophy Image In Situ In Vitro Individual Institutes Institution Interdisciplinary Study International Knowledge Laboratories Leadership Link Lung Malignant Neoplasms Medical Medical Research Medical Students Medicine Mentors Modeling Molecular Medicine Monitor Multimedia Nature Neurosciences Participant Physicians Physiology Population Productivity Prosthesis Proteomics Ramp Reaction Recruitment Activity Registries Research Research Infrastructure Research Methodology Research Personnel Science Scientist Specialized Center Students Thinking Time Training Training Programs Translating Translation Process Translations Underrepresented Minority United States National Institutes of Health Universities Visit base bench to bedside career college design experience high school in vivo innovation interest lymphology peer professor programs role model skills virtual

项目摘要

DESCRIPTION (provided by applicant): The University of Arizona (UA) College of Medicine Diverse Student Medical Research Program (DSMRP) will introduce, train, and nurture inquiring medical and undergraduate students [including under-represented minorities (URM)] in health-related basic/clinical biomedical research (emphasizing cardiovascular, pulmonary, blood); and encourage subsequent intensive/extensive research experiences to retain and strengthen the diverse student researcher pipeline. We will build on the infrastructure, high level of student and faculty mentor participation, esprit-de-corps, and outstanding trainee productivity of our current medical student and disadvantaged high school student programs to bridge the discontinuous diversity pipeline of entering and exiting students as they advance in training and strive for professional/academic careers. Full-time summer-vacation laboratory/clinical investigations will be integrated into an innovative Curriculum on Medical Ignorance (CMI) concentrated in a Summer Institute (SIMI) and sustained through year-round trainee-related enrichment activities. These include topical workshops, clinical correlations, advanced extracurricular research in a Research Honors Distinction Track, Introduction to Molecular Medicine laboratory practicum, a new progressive "Translating Translation" face-to-face/online curriculum interweaving the known and unknown from bench to bedside to community, research methodology/communications/leadership/responsible conduct seminars, visiting professors, and career advising. CMI fosters attitudes and questioning skills to recognize and deal with the vast shifting world of medical ignorance ["what we know we don't know (research), don't know we don't know(discovery), and think we know but don't (error)"]. A unique Virtual Clinical Research Center with Questionarium forms a centerpiece for training and national/international networking. Organized around expanding UA Specialized Centers of Excellence and departments and overseen by Program Director, Basic-Clinical Science Advisors, and faculty-elected Medical Student Research Committee, research encompasses cross-cutting themes and in vivo, in vitro, in situ, in silico, and modeling approaches to the cardiovascular (CV) system and its disorders (cardiac contractility, hypertrophy, development; genomics/proteomics, imaging, biomaterials, prosthetics; endothelial biology, microcirculatory physiology, lymphology, bioengineering); and interdigitating research in cancer, neurosciences, bioinformatics, and other topics of interest to students. Based on our ~30-year track record and access to diverse/disadvantaged populations reflected in 729 medical students and 474 high school students trained to date, we anticipate that DSMRP will cultivate many diverse scientific physician contributors to the research enterprise and a growing cadre of medical scientist leaders to energize the scanty diversity pipeline of healthcare professionals and translational researchers. Detailed S/T and L/T formative/summative program and participant evaluation including database registry, individual development plans, and career portfolios, will document effectiveness and promote networking. PUBLIC HEALTH RELEVANCE: This proposal will develop and implement a model program to recruit, train and mentor a large number of diverse/disadvantaged (including URM) undergraduates and medical students in biomedical research predominantly targeting heart, lung, blood disorders. We will develop a career pipeline to promote retention and career progression, thereby contributing to the NIH Roadmap goals of creating the diverse clinical research teams of the future and advancing translation of medical discoveries from bench to bedside to community.

描述（由申请人提供）：亚利桑那大学（UA）医学院多样化的学生医学研究计划（DSMRP）将在健康相关的基本/临床生物医学研究中介绍，培训和培育医学和本科生（包括代表性不足的基本/临床生物医学研究（包括较低的少数族裔（URM）））并鼓励随后的密集/广泛的研究经验，以保留和加强多样化的学生研究人员管道。我们将建立基础设施，高水平的学生和教师参与，ESPRIT-DE-CORPS以及我们当前的医学生和弱势群体的高中生计划的杰出学员的生产力，以弥合不连续的多样性渠道，即在培训和努力专业/学术职业的培训和努力方面进入学生，并退出学生。全日制夏季实验室/临床研究将纳入集中在夏季学院（SIMI）（SIMI）的医学无知（CMI）的创新课程中，并通过全年与学员相关的富集活动进行维持。其中包括局部研讨会，临床相关性，研究中的高级课外研究，以尊重区别，分子医学实验室实践介绍，一种新的进步的“翻译翻译”面对面/在线/在线课程，与已知的和未知的床头到床头到床头到社区到社区的知名度和未知的课程，研究方法/社区领导力/领导力/负责的行为/责任/负责的行为/访问教授，访问访问者，访问访问者，访问者，访问者，以及访问者，和访问。 CMI促进了态度和质疑技巧，以认识并处理巨大的医学无知世界[“我们所知道的（研究），不知道我们不知道（发现），并认为我们知道但不知道但不知道（错误）”。一个独特的虚拟临床研究中心，构成了用于培训和国家/国际网络的核心。 Organized around expanding UA Specialized Centers of Excellence and departments and overseen by Program Director, Basic-Clinical Science Advisors, and faculty-elected Medical Student Research Committee, research encompasses cross-cutting themes and in vivo, in vitro, in situ, in silico, and modeling approaches to the cardiovascular (CV) system and its disorders (cardiac contractility, hypertrophy, development; genomics/proteomics,成像，生物材料，假肢；以及学生的癌症，神经科学，生物信息学和其他感兴趣的主题的研究。根据我们在729名医学生和474名高中生中反映出的〜30年的往绩并获得了迄今为止培训的474名高中生，我们预计DSMRP将培养许多多样化的科学生理学贡献者，对研究企业以及越来越多的医学科学家领导者的越来越多的医学科学家领导者为医学科学家的领导者提供了越来越多的医学科学研究者，以使医疗服务的多样性研究人员为医疗保健专业的专业人士和翻译专业人士和翻译。详细的S/T和L/T形成/总结计划以及包括数据库注册表，个人发展计划和职业投资组合在内的参与者评估将记录有效性并促进网络。公共卫生相关性：该提案将制定和实施模型计划，以招募，培训和指导大量不同/处境不利的多样性/不利的本科生和医学生，主要针对心脏，肺，血液疾病。我们将开发一条职业渠道来促进保留和职业发展，从而为NIH路线图的目标做出了贡献，即创建了未来的多样化临床研究团队，并将医疗发现从长凳到床边转移到社区的翻译。