Multidisciplinary Psychiatry Genetics Training Program

多学科精神病学遗传学培训计划

• 批准号: 8116495
• 负责人: Elliot S Gershon
• 金额: $ 6.68万
• 依托单位: UNIVERSITY OF CHICAGO
• 依托单位国家: 美国
• 财政年份: 2002
• 资助国家: 美国
• 起止时间: 2002-07-11 至 2012-09-11
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8116495
• 关键词: Genetic; Psychiatry; Training Programs; multidisciplinary

DESCRIPTION (provided by applicant): The central goal of the Departments in this application, Psychiatry, Human Genetics, Neurobiology, Statistics, and Psychology, is generating innovative biomedical research in behavior, the neurosciences, and genetics. This training program has focused on interdisciplinary approaches to genetics of complex inheritance psychiatric disease, including basic research and technology development, since its inception in 2002, with two postdoctoral slots per year. Existing research strengths include molecular genetic research into bipolar illness and schizophrenia, development of transgenic murine models of behavioral disorders and treatment, bioinformatics of DNA sequence and haplotype maps, development of methods for genetic analysis of complex phenotypes, evolutionary and epidemiologic analysis of genetic variation, and microarray methods in clinical investigation. The training program is situated in an environment which encourages interdisciplinary research collaborations. Two types of trainees have been identified and recruited: 1) behavioral health care professionals (MDs or other doctoral degree) with demonstrated potential for a career in pertinent clinical or basic research, such as family studies, genetic epidemiology, and clinical translational research; and 2) PhDs (or MD/PhDs) from appropriate basic and applied science fields, including population genetics molecular and cellular neurobiology, cognitive and systems neuroscience, genetic epidemiology, and physiological psychology. We have been fortunate to fill all available slots with excellent Fellows; three behavioral health care professionals and one basic/translational PhD have completed our program. Additionally, PhD and MD/PhD students who have taken our didactic survey course for credit offer recruitment opportunities for future years. For each trainee, this program includes formal course studies, a series of seminars given by the program faculty, rotation in several laboratories if appropriate at the beginning of the program, and intensive mentored training in their chosen laboratory. Dual clinic/basic mentorship is offered when appropriate. All fellows take the introductory course of the University Clinical Research Training Program, and participate in appropriate graduate courses offered by the Committee on Neurobiology, and the Departments of Psychiatry, Statistics, Health Studies, Psychology and Human Genetics. To foster interactions among the fellows and mentors, trainees give annual seminars and have an opportunity to present their accomplishments at the annual University of Chicago Neuroscience Day. Based on the successes of this program during its initial training period, we request renewal of the T32 grant with increase of the number of Fellowship slots per year from two to three.

描述（由申请人提供）：该申请，精神病学，人类遗传学，神经生物学，统计学和心理学的部门的核心目标是在行为，神经科学和遗传学方面产生创新的生物医学研究。自2002年成立以来，该培训计划一直集中在复杂遗传性精神病遗传学的跨学科方法上，包括基础研究和技术发展，每年有两个博士后插槽。现有的研究优势包括对双极疾病和精神分裂症的分子遗传研究，行为障碍和治疗的转基因鼠模型的发展，DNA序列的生物信息学和单倍型图，开发用于遗传型，进化和流行病学分析的遗传分析的方法，用于遗传变异和微观阶级方法。该培训计划位于鼓励跨学科研究合作的环境中。已经确定和招募了两种类型的学员：1）行为医疗保健专业人员（MDS或其他博士学位），具有相关临床或基础研究职业的潜力，例如家庭研究，遗传流行病学和临床转化研究； 2）来自适当基本和应用科学领域的PHD（或MD/PHD），包括种群遗传学分子和细胞神经生物学，认知和系统神经科学，遗传流行病学以及生理心理学。我们很幸运地用出色的研究员填补了所有可用的老虎机。三名行为医疗保健专业人员和一名基本/转化博士学位已经完成了我们的计划。此外，在未来几年招募了我们的教学调查课程的博士和医学博士学位学生。对于每个学员，该计划包括正式的课程研究，该计划教师的一系列研讨会，如果在计划开始时适当的几个实验室进行轮换，以及他们选择的实验室中的大量指导培训。在适当的时候提供双诊所/基本指导。所有研究员都参加了大学临床研究培训计划的入门课程，并参加了神经生物学委员会提供的适当研究生课程，以及精神病学部门，统计学，健康研究，心理学和人类遗传学。为了培养研究员和导师之间的互动，学员们举行了年度研讨会，并有机会在芝加哥大学一年一度的神经科学日举行成就。根据该计划在其初始培训期间的成功，我们要求续签T32赠款，每年将奖学金插槽数量从两个增加到三。