Consolidated Basic Cancer Research Program

综合基础癌症研究计划

• 批准号: 8111452
• 负责人: RUSSEL E. KAUFMAN
• 金额: $ 12.71万
• 依托单位: WISTAR INSTITUTE
• 依托单位国家: 美国
• 财政年份: 1997
• 资助国家: 美国
• 起止时间: 1997-04-01 至 2014-02-28
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8111452
• 关键词: Appointment; Area; Basic Cancer Research; Basic Science; Biomedical Research; Cancer Biology; Cancer Center; Cancer Center Support Grant; Cancer Research Project; Collaborations; Computational Biology; Etiology; Faculty; Funding; Gene Expression Regulation; Goals; Head; Health; Human; Institutes; Investments; Knowledge; Laboratories; Leadership; Malignant Neoplasms; Mission; Molecular; Molecular Biology; Molecular Immunology; National Cancer Institute; Pathogenesis; Patient Care; Peer Review; Pilot Projects; Positioning Attribute; Principal Investigator; Process; Recording of previous events; Research; Resource Development; Resource Sharing; Resources; Scientific Advances and Accomplishments; Scientist; Shapes; Students; Translational Research; Work; anticancer research; base; cancer genetics; cancer research center director; carcinogenesis; frontier; instrumentation; laboratory facility; member; programs; success; tumor; tumor immunology; tumorigenesis; virology

DESCRIPTION (provided by applicant): In the early 1960's Wistar's scientists began to devote increasing efforts to cancer research. Significant advances were made in tumor virology, carcinogenesis, and molecular biology, led by Drs. Vittorio Defendi, Barbara Knowles, and Carlo M. Croce. In recognition of this increased focus on cancer research, Wistar received a Cancer Center Support Grant (CCSG) and was designated by the National Cancer Institute (NCI) as a federally designated Cancer Center in 1972, specializing in basic research. The Institute has had over 40 years of continuous funding from the NCI with a history of significant advances in cancer genetics, cancer biology, and tumor immunology and virology. The Cancer Center receives $11,582,210 of total funding from the NCI, amounting to over 50% of total federal peer reviewed funding, attesting to the cancer focus of the Center. The Cancer Center is organized to develop and support Cancer Center members, research programs, and the Shared Facilities. Each laboratory in the Cancer Center is headed by a principal investigator who has an active research program at the Institute. The Cancer Center is headed by a Director and two Deputy Directors. Dr. Kaufman is the Director of the Cancer Center and has ultimate control of space, financial resources, appointments, and staff positions in the Cancer Center. Drs. Frank J. Rauscher III and Meenhard Herlyn serve as the Cancer Center's Deputy Directors. Dr. Rauscher's primary responsibility is promotion of basic science research, while Dr. Herlyn provides leadership in the area of translational research. The Cancer Center has made significant progress over the course of the last funding period with recruitment of 12 scientists, renovation of Cancer Center laboratory space, extensive renovation and investment in new instrumentation in shared facilities, and development of resources and plans to expand laboratory facilities. Most importantly, we have made major scientific advances in the fields of cancer genetics, cancer biology, computational biology, and tumor immunology.

描述（由申请人提供）：在1960年代初期，Wistar的科学家开始将越来越多的努力投入到癌症研究上。由DRS领导的肿瘤病毒学，癌变和分子生物学取得了重大进展。 Vittorio Defendi，Barbara Knowles和Carlo M. Croce。为了认识到这种对癌症研究的关注，Wistar获得了癌症中心支持补助金（CCSG），并于1972年被国家癌症研究所（NCI）指定为联邦指定的癌症中心，专门研究基础研究。该研究所已经从NCI获得了超过40年的持续资金，并在癌症遗传学，癌症生物学以及肿瘤免疫学和病毒学方面取得了重大进展的历史。癌症中心从NCI获得了总资金的11,582,210美元，总计超过联邦同行审查的资金的50％以上，证明了该中心的癌症重点。组织癌症中心旨在开发和支持癌症中心成员，研究计划和共享设施。癌症中心的每个实验室都由该研究所拥有活跃研究计划的首席研究员领导。癌症中心由董事和两名副董事领导。考夫曼博士是癌症中心主任，对癌症中心的空间，财务资源，任命和员工职位具有最终控制。博士。弗兰克·J·劳斯三世（Frank J. Rauscher博士的主要责任是促进基础科学研究，而Herlyn博士在转化研究领域提供领导。 癌症中心在最后一个资金期间取得了重大进展，招募了12位科学家，对癌症中心实验室空间进行翻新，对共享设施的新工具进行了广泛的翻新和投资，并开发了扩大实验室设施的资源和计划。最重要的是，我们在癌症遗传学，癌症生物学，计算生物学和肿瘤免疫学领域取得了重大科学进步。