CORE--DIAGNOSTIC SCREENING LABORATORY

核心——诊断筛查实验室

• 批准号: 6109626
• 负责人: RUSSEL E. KAUFMAN
• 金额: $ 11.39万
• 依托单位: DUKE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 1997
• 资助国家: 美国
• 起止时间: 1997-04-01 至 2000-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6109626
• 关键词: biomedical facility; blood disorder diagnosis; genotype; human subject; mass screening; phenotype; sickle cell anemia

The Diagnostic Laboratory of the Duke Comprehensive Sickle Cell Center has been organized to provide accurate phenotypic and genotypic data on patients being studied at the Center. Because of the considerable heterogeneity in the clinical course of sickle cell patients and among individual cells in the blood of patients with sickle cell disease, clinical and basic laboratory research requires an understanding of the patients or blood samples being examined. The laboratory also has the responsibility for developing protocols to effectively communicate this information to the investigators using the information and to develop approaches that will ultimately lead to improved algorithms for care for patients with sickling disorders.

杜克大学综合镰状细胞中心的诊断实验室 已经组织了以提供准确的表型和基因型数据 患者在中心学习。 因为很大 镰状细胞患者的临床过程中的异质性以及 镰状细胞疾病患者血液中的个体细胞， 临床和基础实验室研究需要了解 检查患者或血液样本。 实验室也有 制定协议有效传达的责任 使用信息向调查人员提供信息并开发 最终会导致改进算法护理的方法 患病障碍的患者。