Houston Area Molecular Biophysics Program

休斯顿地区分子生物物理学计划

• 批准号: 8101141
• 负责人: THEODORE G WENSEL
• 金额: $ 35.9万
• 依托单位: BAYLOR COLLEGE OF MEDICINE
• 依托单位国家: 美国
• 财政年份: 1988
• 资助国家: 美国
• 起止时间: 1988-09-30 至 2014-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8101141
• 关键词: Area; Biophysics; Molecular; programs

DESCRIPTION (provided by applicant): The Houston Area Molecular Biophysics Program (HAMBP) is a Ph.D. research training program in molecular biophysics involving 43 faculty mentors in six educational/research institutions in the Houston- Galveston area: Baylor College of Medicine, Rice University, University of Houston, University of Texas Health Science Center at Houston, University of Texas M.D. Anderson Cancer Center, and University of Texas Medical Branch at Galveston. Because of the large number of faculty, and the large and diverse applicant pool represented by this group of institutions, we propose to maintain our number of funded trainees at 9. Students pursue a rigorous course of study in the classroom and in the laboratory. Program activities required of all trainees include didactic courses in Molecular Biophysics and responsible conduct of research, a weekly seminar, monthly trainee meetings, an annual research symposium and progress review, and attendance and presentation at two annual research conferences. They receive a strong foundation in the fundamentals-of Molecular Biophysics, with exposure to a broad range of topics, and pursue cutting-edge thesis research in world-class biophysics laboratories. Research areas include x-ray crystallography, macromolecular electron microscopy, fluorescence, magnetic resonance and other types of macromolecular spectroscopy, thermodynamics, kinetics, molecular dynamics, theoretical biophysics, protein folding, nucleic acid structure, molecular recognition, and others. Biological structures studied range in size from peptides and lipid mediators to viruses, transcription complexes, and muscle filaments. Supported trainees have included 5 underrepresented minorities, and have had average GRE scores of 78%tile (Q), 82%tile (A), 74%tile(V), with average undergraduate GPAs of 3.50/4.0. The average time-to-degree of the 29 students supported in the last 10 years who have completed their Ph.D. is 5.27 years. The average number of publications per trainee is 3.8 for graduated trainees, including many high-profile papers and journal covers. Alumni have secured excellent positions upon completion of training, and continue to perform research at a high level. The Program is administered by a Steering Committee of representatives from all partner institutions, which closely monitors the progress of trainees, and make decisions about admission of applicant students and mentors. HAMBP is one of several highly successful cooperative training and research ventures of the partner institutions, which together represent a larger pool of research resources and trainees than any single institution in the U.S. RELEVANCE: Training in Molecular Biophysics enables research careers leading to fundamental understanding of human disease and development of innovative approaches to diagnostics, therapeutics, and disease prevention. Biophysics provides tools used by all specialties in biomedical research and in medical practice

描述（由申请人提供）：休斯顿地区分子生物物理学计划（HAMBP）是博士学位。在休斯顿加尔维斯顿地区的六家教育/研究机构中，涉及43位教职员工的分子生物物理学研究培训计划：赖斯大学贝勒医学院，赖斯大学，休斯顿大学，德克萨斯大学健康科学中心，休斯敦，德克萨斯大学M.D. Anderson癌症中心，以及德克萨斯大学癌症中心，以及德克萨斯大学医学院。由于这一机构代表的大量教职员工以及大型多样的申请人池，我们建议将我们的资助学员数量保持在9。学生在课堂和实验室中进行严格的学习课程。所有受训者所需的计划活动包括分子生物物理学的教学课程和负责任的研究，每周一次研讨会，每月的学员会议，年度研究研讨会和进度评论，以及在两次年度研究会议上的出席和演讲。他们在分子生物物理学的基础上获得了强大的基础，并遭受了广泛的主题，并在世界一流的生物物理实验室中追求最先进的论文研究。研究领域包括X射线晶体学，大分子电子显微镜，荧光，磁共振和其他类型的大分子光谱，热力学，动力学，动力学，分子动力学，理论生物物理学，蛋白质折叠，核酸结构，分子识别等。研究的生物结构范围从肽和脂质介质到病毒，转录复合物和肌肉丝的大小范围。受支持的学员包括5个代表性不足的少数族裔，平均GRE得分为78％（Q），瓷砖为82％（a），瓷砖为74％（V），平均本科GPA为3.50/4.0。在过去的10年中，获得博士学位的29名学生的平均时间是学位。是5。27年。毕业生的平均每学员出版物数量为3.8，包括许多备受瞩目的论文和期刊封面。校友在完成培训后确保了出色的职位，并继续高水平进行研究。该计划由所有合作伙伴机构的代表指导委员会管理，该机构密切监视受训者的进步，并决定接受申请人和导师的录取。 HAMBP是合作伙伴机构的几项非常成功的合作培训和研究事业之一，与美国相关的任何一个机构相比，它们共同代表了更大的研究资源和受训者：分子生物物理学的培训使研究职业能够使人类疾病的基本了解以及对诊断，治疗方法和预防诊断，治疗方法的发展。生物物理学提供了所有专业在生物医学研究和医学实践中使用的工具