COBRE: UVM: CORE D: TRANSLATIONAL NEUROSCIENCE TRAINING

COBRE：UVM：核心 D：转化神经科学培训

• 批准号: 7381248
• 负责人: FELIX P ECKENSTEIN
• 金额: $ 16.79万
• 依托单位: UNIVERSITY OF VERMONT & ST AGRIC COLLEGE
• 依托单位国家: 美国
• 财政年份: 2006
• 资助国家: 美国
• 起止时间: 2006-07-01 至 2007-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7381248
• 关键词: Parkinson' s disease; anatomy; career; clinical research; colon; medicine; multiple sclerosis; nervous system disorder; neurobiology; neurosurgery; psychology; publications; reading; schizophrenia; serotonin; success; university

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. This Core is in its 4th year of support, with the goal to provide an intellectual environment encouraging career development in translational neuroscience. Previously, the core had provided the stipend to support a research fellowship for two medical students (Coates and Kelley) who conducted full-time bench research with Drs. Mawe and Wellman. Mr. Coates¿ published one paper and presented at national meetings. This success motivated Mr. Coates to enter UVM¿s MD/PhD program. Mr. Kelley has graduated and is currently a resident at the University of North Carolina. During the year the core provided additional fellowship support for two medical students (Ciolino and Quick). These students have conducted research with Drs. Mawe and Cipolla. Ms. Quick's work has resulted in one published paper and Ms. Ciolino is continuing her fellowship. This year, Ms. Chuan-Ju Pan is conducting research in Dr. Eckenstein's laboratory, and it is expected that she will co-author two publications. Additionally, this year Dr. Meagan Costedio is conducting research in Dr. Gary Mawe's lab. Her research consists of a project to determine if serotonin concentrations and signaling are altered in the colons of people with diverticulosis, and how they compare with colons of people with diverticulitis. A course illustrating the progress of translational neuroscience research has been organized. The course provides an in-depth analysis of research into a single neurological disease. The disease to be covered changes every year. Past disease entities covered include Parkinson's Disease, Multiple Sclerosis and Schizophrenia. This year's course will focus on Amyotrophic Lateral Sclerosis. The course consists of 12 weekly sessions ranging from clinical research to basic molecular approaches. Faculty from the Departments of Neurology, Neurosurgery, Psychology, Medicine and Anatomy & Neurobiology collaborate in this team-taught course. In addition, two outside speakers contributed lectures this year. An Undergraduate Neuroscience Summer fellowship program has been established. Undergraduates perform 10 weeks of research, read primary literature and attend lectures given by COBRE faculty. Approximately 40 students (most from institutions different from UVM) apply, and approximately 8 are selected. Several have gone on to Ph.D. graduate programs.

该子项目是利用 NIH/NCRR 资助的中心拨款提供的资源的众多研究子项目之一，该子项目和研究者 (PI) 可能已从其他 NIH 来源获得主要资助，因此可以在其他 CRISP 机构中得到体现。列出的是该中心，该中心不一定是研究者的机构。该核心已进入第四年的支持，其目标是提供一个鼓励转化神经科学职业发展的知识环境，此前，该核心曾为研究者提供过津贴。支持为两名与 Mawe 和 Wellman 先生一起进行全职实验室研究的医学生（Coates 和 Kelley）提供研究奖学金。发表了一篇论文并在全国会议上发表了演讲，这一成功激励 Coates 先生进入 UVM。凯利先生已毕业，目前是北卡罗来纳大学的住院医师。这一年，该中心为两名医学生（Ciolino 和 Quick）提供了额外的支持。 Mawe 和 Cipolla 女士的工作发表了一篇论文，Ciolino 女士将继续她的研究金。今年，Chuan-Ju Pan 女士正在 Eckenstein 博士的实验室进行研究，预计她将继续进行研究。此外，Meagan Costedio 博士今年正在 Gary Mawe 博士的实验室进行研究，她的研究项目旨在确定憩室病患者结肠中的血清素浓度和信号是否发生改变，以及它们是如何改变的。与憩室炎患者的结肠进行比较。该课程对单一神经系统疾病的研究进行了深入分析。过去的疾病实体包括帕金森病、多发性硬化症和精神分裂症。今年的课程将重点关注肌萎缩性脊髓侧索硬化症。该课程每周包括 12 节课程，涵盖神经内科、神经外科、神经外科等部门的课程。心理学、医学以及解剖学和神经生物学在这门团队授课的课程中合作。此外，今年还开设了本科生神经科学暑期奖学金项目。本科生进行 10 周的研究，阅读主要文献并参加 COBRE 教师的讲座。大约 40 名学生（大多数来自 UVM 以外的机构）提出申请，其中大约 8 名学生被选中继续攻读博士学位。 。