Autoimmunity and Immunopathology Training Program

自身免疫和免疫病理学培训计划

基本信息

项目摘要

DESCRIPTION (provided by applicant): This is a new training program in Autoimmunity and Immunopathology at the University of Pittsburgh School of Medicine. We believe that research in autoimmunity and immunopathology provides challenging and exciting opportunities for young scientists. Adequate training requires intense exposure to contemporary concepts in immunology and clinical aspects of immunopathology. The goal of this proposed training program in autoimmunity and immunopathology is to produce outstanding trainees (four predoctoral and three postdoctoral) with the ability to perform interdisciplinary, cutting-edge research. We will build on the existing strengths in translational research here at the University of Pittsburgh. In addition, new recruits to the University of Pittsburgh with expertise in the area of autoimmunity research mean that there is now a critical mass of investigators to provide this much needed training program. Several of our faculty are engaged in preclinical studies which are then tested in the clinic. We will achieve this by bringing together faculty and trainees performing research related to autoimmunity and immunopathology (immunology, cell biology, molecular genetics and clinical rheumatology). The proposed program is within the framework of a large. Interdisciplinary Biomedical Graduate Program (IBGP) based in the University of Pittsburgh, School of Medicine that encourages interactions among several disciplines and that enables trainees to master different fields of contemporary biology. The proposed program also draws from the established Immunology (IMM) Graduate Program and additional faculty in several University of Pittsburgh clinical departments, including the Arthritis Institute. The IMM graduate programs consist of faculty from several departments in the School of Medicine, and together with the specialized training provided by the Arthritis Institute, offer a comprehensive range of formal introductory and specialized courses that will afford unified training in autoimmunity and immunopathology. This proposed training program is enabled and supported by faculty with strong records as trainers in autoimmunity, immunopathology and related areas of research, recently- expanded facilities, and strong Institutional support at the University of Pittsburgh. RELEVANCE (See instructions): The increasing incidence of autoimmune and immunopathological conditions coupled with a lack of effective therapies for many of these diseases highlights the need to recruit young scientists to choose a career in investigating these diseases. This program will also address the national shortage of physician-scientists entering the field of rheumatology and related disciplines.
描述(由申请人提供):这是匹兹堡大学医学院的自身免疫和免疫病理学的新培训计划。我们认为,自身免疫性和免疫病理学的研究为年轻科学家提供了具有挑战性和令人兴奋的机会。足够的培训需要在免疫病理学的免疫学和临床方面强烈接触当代概念。该提议的自身免疫性和免疫病理学培训计划的目标是生产出色的学员(四名前术和三个博士后),能够进行跨学科的,尖端的研究。我们将基于匹兹堡大学转化研究的现有优势。此外,匹兹堡大学的新兵在自身免疫研究领域具有专业知识,这意味着现在有大量的调查人员可以提供这项急需的培训计划。我们的一些教职员工从事临床前研究,然后在诊所进行了测试。我们将通过将与自身免疫性和免疫病理学有关的研究(免疫学,细胞生物学,分子遗传学和临床风湿病学)进行研究来实现这一目标。拟议的程序在大的框架内。位于匹兹堡大学的跨学科生物医学研究生计划(IBGP),鼓励几个学科之间的互动,这使学员能够掌握当代生物学的不同领域。拟议的计划还借鉴了匹兹堡大学的几个临床系(包括关节炎研究所)的既定免疫学(IMM)研究生课程和其他教职员工。 IMM研究生课程包括来自医学院多个部门的教职员工,以及关节炎研究所提供的专门培训,提供了一系列正式的入门和专业课程,这些课程将负担自身免疫和免疫病理学的统一培训。这项提出的培训计划得到了教师的支持和支持,并在匹兹堡大学的自身免疫性,免疫病理学及相关研究领域,最近扩展的设施以及强大的机构支持方面拥有强大的记录。 相关性(请参阅说明):自身免疫性和免疫病理状况的发生率不断增加,加上缺乏这些疾病的有效疗法,这突显了需要招募年轻科学家选择研究这些疾病的职业的必要性。该计划还将解决进入风湿病和相关学科领域的医师科学家的全国短缺。

项目成果

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Penelope Anne Morel其他文献

Penelope Anne Morel的其他文献

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{{ truncateString('Penelope Anne Morel', 18)}}的其他基金

Akt controls alternative splicing in T helper call fate decisions
Akt 控制 T 辅助细胞命运决定中的选择性剪接
  • 批准号:
    10062858
  • 财政年份:
    2017
  • 资助金额:
    $ 36.43万
  • 项目类别:
Akt controls alternative splicing in T helper call fate decisions
Akt 控制 T 辅助细胞命运决定中的选择性剪接
  • 批准号:
    10304165
  • 财政年份:
    2017
  • 资助金额:
    $ 36.43万
  • 项目类别:
Autoimmunity and Immunopathology Training Program
自身免疫和免疫病理学培训计划
  • 批准号:
    8486378
  • 财政年份:
    2010
  • 资助金额:
    $ 36.43万
  • 项目类别:
Autoimmunity and Immunopathology Training Program
自身免疫和免疫病理学培训计划
  • 批准号:
    8301677
  • 财政年份:
    2010
  • 资助金额:
    $ 36.43万
  • 项目类别:
Autoimmunity and Immunopathology Training Program
自身免疫和免疫病理学培训计划
  • 批准号:
    8668887
  • 财政年份:
    2010
  • 资助金额:
    $ 36.43万
  • 项目类别:
Autoimmunity and Immunopathology Training Program
自身免疫和免疫病理学培训计划
  • 批准号:
    7941327
  • 财政年份:
    2010
  • 资助金额:
    $ 36.43万
  • 项目类别:
BD FACSARIA FLOW CYTOMETER: INFECTIOUS DIS: TB, LUNG, CHAGAS, HSV KERATITIS, PNE
BD FACSARIA 流式细胞仪:感染性疾病:结核病、肺病、南美锥虫病、HSV 角膜炎、PNE
  • 批准号:
    6973421
  • 财政年份:
    2004
  • 资助金额:
    $ 36.43万
  • 项目类别:
BD FACSARIA FLOW CYTOMETER: AUTOIMMUNE DIS & GENETICS: DIABETES, RHEUMATOID ARTH
BD FACSARIA 流式细胞仪:自身免疫 DIS
  • 批准号:
    6973423
  • 财政年份:
    2004
  • 资助金额:
    $ 36.43万
  • 项目类别:
BD FACSARIA FLOW CYTOMETER 3 LSR
BD FACSARIA 流式细胞仪 3 LSR
  • 批准号:
    6731393
  • 财政年份:
    2004
  • 资助金额:
    $ 36.43万
  • 项目类别:
BD FACSARIA FLOW CYTOMETER: CANCER, LYMPHOMA, MYELOMA
BD FACSARIA 流式细胞仪:癌症、淋巴瘤、骨髓瘤
  • 批准号:
    6973420
  • 财政年份:
    2004
  • 资助金额:
    $ 36.43万
  • 项目类别:

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Single-cell dissection of CD4 T cell changes in patients with immune-related adverse events following PD-1 inhibition
PD-1 抑制后出现免疫相关不良事件的患者 CD4 T 细胞变化的单细胞解剖
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    10571532
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大脑常驻记忆T细胞的功能和调节
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Function and regulation of brain resident memory T cells
大脑常驻记忆T细胞的功能和调节
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    9870360
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    2021
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    $ 36.43万
  • 项目类别:
Autoimmunity and Immunopathology Training Program
自身免疫和免疫病理学培训计划
  • 批准号:
    8486378
  • 财政年份:
    2010
  • 资助金额:
    $ 36.43万
  • 项目类别:
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