Replacement of Microscopy Core 10-years-old Zeiss LSM-510 with a new LSM-710

用新的 LSM-710 更换使用了 10 年的蔡司 LSM-510 显微镜核心

• 批准号: 7791774
• 负责人: PHONG T TRAN
• 金额: $ 44.21万
• 依托单位: UNIVERSITY OF PENNSYLVANIA
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-08-01 至 2011-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7791774
• 关键词: 10 year old; Back; Charge; Contract Services; Core Facility; Developmental Cell Biology; Ensure; Equipment; Equus caballus; Fees; Funding; Grant; Laboratories; Lasers; Manufacturer Name; Microscope; Microscopy; Mission; Occupations; Pennsylvania; Productivity; Publications; Research; Research Personnel; Scanning; Security; Training; United States National Institutes of Health; Universities; Wages; Work; biomedical scientist; instrument; medical schools

DESCRIPTION (provided by applicant): The Department of Cell & Developmental Biology of the University of Pennsylvania School of Medicine established a Microscopy Core facility in 2006. The mission of the Core is to train and assist biomedical scientists, both departmental and University-wide, in the application of microscopy to their research. The daily activity of the Core is overseen by Dr. Andrea Stout (Director) and Dr. Yuri Veklich (Manager). Users are charged a modest fee for the use of the instruments of the Core. In turn, the money generated is put back into the Core as equipment service contracts, supplies, or salary support for Drs. Stout and Veklich. The Core brought together several microscopes under one administrative roof, the center piece of which is a Zeiss LSM-510 laser scanning confocal microscope purchased in 1998 with a NIH SIG grant (PI: Dr. John Murray). This microscope has been a work-horse for more than 10 years, has contributed to the research of more than 30 NIH-funded laboratories, and has directly resulted in over 100 publications. Due to normal wear-and-tear during the past ten years, this microscope is no longer operating at optimal efficiency and some parts are no longer supported by the manufacturer. We now request funds to replace the LSM-510 with its current version LSM-710. The new microscope will ensure continued usage and productivity from the researchers, and thus maintain job security and microscopy-training mission of Drs. Stout and Veklich.

描述（由申请人提供）：宾夕法尼亚大学医学院的细胞与发育生物学系于2006年建立了一个显微镜核心设施。核心的使命是培训和协助显微镜在其研究中应用于系范围的生物医学科学家。核心的日常活动由Andrea Stout博士（主任）和Yuri Veklich博士（经理）监督。用户收取适度的费用，用于使用核心的仪器。反过来，作为设备服务合同，用品或DRS的薪水支持，所产生的资金被重新放回核心。粗壮和Veklich。核心将几个行政屋顶下的几个显微镜汇总在一起，其中心是Zeiss LSM-510激光扫描共聚焦显微镜，于1998年购买了NIH Sig Grant（PI：John Murray博士）。该显微镜已经是一只工作马已有10多年了，为30多个NIH资助的实验室的研究做出了贡献，并直接导致了100多个出版物。由于过去十年来正常的磨损，该显微镜不再以最佳效率运行，并且制造商不再支持某些零件。现在，我们要求资金用当前版本的LSM-710替换LSM-510。新的显微镜将确保研究人员的持续使用和生产力，从而维持DR的工作安全和显微镜培训任务。粗壮和Veklich。