Genitourinary Oncology

泌尿生殖肿瘤学

• 批准号: 7944549
• 负责人: ALLAN J PANTUCK
• 金额: $ 7.72万
• 依托单位: UNIVERSITY OF CALIFORNIA LOS ANGELES
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-04-02 至 2013-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7944549
• 关键词: Antineoplastic Agents; Area; Award; Basic Science; Cancer Center; Cancer Center Support Grant; Caring; Clinical; Clinical Research; Clinical Trials; Collaborations; Community Clinical Oncology Program; Development; Education; Evaluation; Extramural Activities; Faculty; Financial Support; Fostering; Funding; Genitourinary system; Gifts; Goals; Grant; Group Meetings; Growth and Development function; Healthcare; Jonsson Comprehensive Cancer Center of University of California Los Angeles; Journals; Kidney; Knockout Mice; Leadership; Malignant Neoplasms; Malignant neoplasm of urinary bladder; Molecular; Neoplasm Metastasis; Outcome; Patients; Peer Review; Phase; Prevention; Prostate; Publications; Reproduction spores; Research; Research Personnel; Research Project Grants; Resource Sharing; Seeds; Signal Transduction; Therapeutic Agents; Transgenic Organisms; Translating; Translational Research; Urogenital Cancer; Xenograft procedure; anticancer research; base; bench to bedside; innovation; interest; member; mouse model; novel; novel therapeutics; oncology; pre-clinical; preclinical study; programs; treatment strategy

The Genitourinary Oncology Program Area is composed of 18 members, spanning 9 Departments within UCLA. In the past competing cycle, investigators from this Program authored 328 publications, of which 167 (51%) were inter-programmatic and 190 (58%) intra-programmatic. 96 (29%) were placed in high-impact ournals. 11 members of this Program Area used 8 out of the 8 JCCC Shared Resources. Peer-reviewed Funding for this program totals $8.7M of which $4.3M is awarded from NCI. As with other Program Areas, JCCC fosters a number of interactive activities and many of the Shared Resources that support investigators in the GU Program Area. During the current grant cycle, funds from the JCCC in the form of CCSG Developmental Funds, institutional support and philanthropic gifts to the GU Program Area total $1,001,382. These funds supported Seed Grants, recruitment/retention, Program Area Leadership support, funding for the use of emerging Shared Resources and trainees. Twelve of the Program Area Members were the recipients of JCCC support. ($500K of these funds were in support of the UCLA Prostate SPORE. These funds were then used to support SPORE-related activities which benefited a larger group of faculty, some of whom are JCCC Members.) The Program seeks to coordinate all clinical activities to deliver optimum care to patients with localized and metastatic tumors. Furthermore, the Program hopes to facilitate the study of new and emerging treatment strategies, especially those translated from basic science research. The goals of the GU Oncology Program are: 1) Creating mouse models of these cancers; 2) Perform pre-clinical studies of new therapeutic agents; and 3) Conduct phase l/ll clinical trials of novel anti-cancer drugs.

泌尿生殖肿瘤学项目领域由 18 名成员组成，涵盖 9 个科室 加州大学洛杉矶分校。在过去的竞争周期中，该计划的研究人员撰写了 328 篇出版物，其中 167 篇 (51%) 是项目间的，190 (58%) 是项目内的。 96 (29%) 被安置在高影响力 期刊。该计划领域的 11 个成员使用了 8 个 JCCC 共享资源中的 8 个。同行评审 该项目的资金总额为 870 万美元，其中 430 万美元由 NCI 资助。与其他计划领域一样， JCCC 促进了许多互动活动和许多支持调查人员的共享资源 在 GU 计划区。在当前拨款周期内，JCCC 以 CCSG 的形式提供资金 向 GU 计划领域提供的发展基金、机构支持和慈善捐赠总额为 1,001,382 美元。 这些资金支持种子补助、招募/保留、计划领域领导支持、资助 使用新兴的共享资源和学员。十二名计划领域成员是 JCCC 支持的接受者。 （其中 50 万美元用于支持 UCLA 前列腺 SPORE。这些资金 然后，资金被用于支持与 SPORE 相关的活动，这些活动使更多的教职人员受益，其中一些 谁是 JCCC 会员。） 该计划旨在协调所有临床活动，为患有局部和慢性疾病的患者提供最佳护理。 转移性肿瘤。此外，该计划希望促进新兴治疗方法的研究 战略，尤其是那些从基础科学研究转化而来的战略。 GU 肿瘤学计划的目标 是：1）创建这些癌症的小鼠模型； 2) 进行新治疗药物的临床前研究； 3）开展新型抗癌药物的l/ll期临床试验。