2022 & 2024 Drug Resistance Gordon Research Conference and Seminar

2022年

• 批准号: 10468465
• 负责人: Lizbeth K. Hedstrom
• 金额: $ 0.55万
• 依托单位: GORDON RESEARCH CONFERENCES
• 依托单位国家: 美国
• 财政年份: 2022
• 资助国家: 美国
• 起止时间: 2022-06-15 至 2023-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10468465
• 关键词: Address; Agriculture; Anti-Bacterial Agents; Antifungal Agents; Antineoplastic Agents; Antiparasitic Agents; Antiviral Agents; Area; Award; Collaborations; Communicable Diseases; Communities; Country; Discipline; Disease; Drug Design; Drug resistance; Empathy; Environment; Face; Foundations; Geography; Goals; Government; Herbicides; Hour; Industry; Insecta; Insecticides; Institution; Investigation; Life Expectancy; Malignant Neoplasms; Methodology; Mind; Modeling; Modernization; Organism; Pharmaceutical Preparations; Physicians; Postdoctoral Fellow; Request for Proposals; Research; Research Personnel; Resistance; Resistance development; Risk-Taking; Science; Scientist; System; Techniques; Time; Travel; Woman; Work; career; combat; coronavirus disease; drug resistant pathogen; experience; graduate student; meetings; microbiome; novel; novel strategies; pesticide resistance; posters; programs; recruit; resistance mechanism; response; success; symposium; Address; Agriculture; Anti-Bacterial Agents; Antifungal Agents; Antineoplastic Agents; Antiparasitic Agents; Antiviral Agents; Area; Award; Collaborations; Communicable Diseases; Communities; Country; Discipline; Disease; Drug Design; Drug resistance; Empathy; Environment; Face; Foundations; Geography; Goals; Government; Herbicides; Hour; Industry; Insecta; Insecticides; Institution; Investigation; Life Expectancy; Malignant Neoplasms; Methodology; Mind; Modeling; Modernization; Organism; Pharmaceutical Preparations; Physicians; Postdoctoral Fellow; Request for Proposals; Research; Research Personnel; Resistance; Resistance development; Risk-Taking; Science; Scientist; System; Techniques; Time; Travel; Woman; Work; career; combat; coronavirus disease; drug resistant pathogen; experience; graduate student; meetings; microbiome; novel; novel strategies; pesticide resistance; posters; programs; recruit; resistance mechanism; response; success; symposium

PROJECT SUMMARY The prosperity of the modern world is threatened by the relentless emergence of drug-resistant pathogens, pesticide-resistant insects and herbicide-resistant weeds. New investigational cancer drugs increase life expectancy, but inevitably fail when resistance develops. Although the threat of resistance is shared, the fields of infectious disease, cancer and agriculture have largely responded independently. Work on resistance is typically siloed in organism-specific conferences- even within infectious diseases, scientists working on antibacterials, antifungals, antiparasitics, and antivirals rarely communicate. The 2022 Gordon Research Conference on Drug Resistance uniquely bring together scientists studying infectious disease, anticancer agents, insecticides and herbicides to discuss the common threat of resistance. We are requesting partial support for these conferences to defray registration and travel expenses for speakers and select attendees, specifically early career investigators, post docs and graduate students. Our goal is to mount a program of 36 speakers, 8-12 chosen from poster abstracts, with 9 sessions describing recent advances in the field. The opening/closing keynote sessions will be (1) Challenges and Opportunities of Understanding Resistance Mechanisms in Agriculture and (9) Emerging Strategies to Combat Resistance. Other sessions will include (2) Mechanisms of Resistance, (3) Systems and Modeling Strategies to Address Resistance, (4) Combating Resistance with Novel Targets, (5) Durable Drug Design, (6) Eco-Evolutionary Strategies to Address Resistance, (7) Threats and Responses and (8) The Microbiome and Resistance. The speakers and discussion leaders will be recruited from across the fields of infectious disease, cancer and agriculture, drawn from academics, government organizations, foundations and industry (both small and large). We will also aggressively recruit a mix of attendees from many different countries and institutions, with diverse expertise, new perspectives and open minds because the success of this conference relies on abroad representation of disciplines, varying seniority, and wide geographic and cultural perspectives. All attendees will have the option of presenting their work during afternoon poster sessions and junior investigators will also have the opportunity to attend an associated Gordon Research Seminar. The meeting will also include a GRC Power hour to discuss and address the challenges women face in the field.

项目摘要 现代世界的繁荣受到抗药性的不懈兴趣的威胁 病原体，抗杀虫剂的昆虫和抗除草剂的杂草。新调查 癌症药物会增加预期寿命，但不可避免地会发生抵抗时失败。虽然 抵抗的威胁是共享的，传染病，癌症和农业领域 在很大程度上做出了独立反应。在有机体特异性中，抗性的工作通常是孤立的 会议 - 即使在传染病中，从事抗菌，抗真菌剂的科学家， 反寄生虫和抗病毒药很少交流。 2022年戈登研究会议 耐药性独特地汇集了研究传染病，抗癌的科学家 特工，杀虫剂和除草剂讨论抗药性的常见威胁。我们是 要求部分支持这些会议，以支付注册和旅行费用 演讲者和精选与会者，特别是早期职业调查人员，邮政文件和研究生 学生。我们的目标是安装一个由36位演讲者组成的程序，从海报摘要中选择8-12个， 有9次会议描述了该领域的最新进展。开放/结束主题演讲 将是（1）理解抵抗机制的挑战和机会 农业和（9）新兴策略以对抗抵抗力。其他会议将包括（2） 电阻机制，（3）系统和建模策略以解决电阻，（4） 用新目标对抗抗性，（5）耐用药物设计，（6）生态进化 应对抵抗，（7）威胁和反应的策略以及（8）微生物组和 反抗。演讲者和讨论负责人将在整个领域招募 传染病，癌症和农业，由学者，政府组织汲取 基金会和工业（大小不一）。我们还将积极招募 来自许多不同国家和机构的参与者，具有多样的专业知识，新的 观点和开放的思想，因为这次会议的成功依赖于国外 代表学科，不同的资历以及广泛的地理和文化观点。 所有与会者都可以选择在下午的海报会议上介绍他们的工作， 初级调查人员还将有机会参加相关的戈登研究 研讨会。会议还将包括一个GRC力量时刻，讨论和解决 挑战妇女在现场面临的挑战。