BIOMECHANICS CORE

生物力学核心

基本信息

批准号：
7802705
负责人：
JAMES Anthony ASHTON-MILLER
金额：
$ 12.84万
依托单位：
UNIVERSITY OF MICHIGAN AT ANN ARBOR
依托单位国家：
美国
项目类别：
财政年份：
2009
资助国家：
美国
起止时间：
2009-09-30 至 2014-08-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/7802705
关键词：
Affect Age Aging American Area Biomechanics Centers for Disease Control and Prevention (U.S.)Characteristics Collaborations Computer Simulation Deterioration Diagnosis Diagnostic tests Discipline Elderly Equilibrium Exercise Faculty Female Fostering Functional disorder Funding Future Gait Goals Impairment Individual Injury Life Maintenance Measurement Mentorship Methods Mission Muscle Contraction Musculoskeletal Equilibrium Neurologic Patients Pelvic floor structure Phenotype Physiological Pilot Projects Prevention Prevention Protocols Process Protocols documentation Ptosis Published Comment Research Research Personnel Research Training Role Services Surface Syndrome Technical Expertise Technology Transfer Testing Training Urethra Urinary Incontinence aged bench to bedside career development data acquisition design disability effective therapy experience falls injury prevention insight interest motor control programs ranpirnase response sphincter ani muscle structure

项目摘要

Whatever the underlying physiologic or neurologic mechanisms, questions about loss of mobility, deterioration of motor control, responses to impending falls, maintenance of balance and postural control, changes in muscle contraction characteristics and maintenance of continence are ultimately biomechanical questions (Ashton-Miller & Alexander, 2003). The facilities of the Biomechanics Core will enable examination of such questions quantitatively, from the viewpoint of biomechanics and other physiological measurements. In particular the Biomechanics Core will contribute to the mission of the UM Pepper Center by fostering research Into the mechanisms by which certain predictor and modifying variables earlier in life may affect the expression of aged phenotypes. Applications of Biomechanics Research: There is ample justification for funding research and research training that help examine the role of biomechanical and other physiological mechanisms that contribute to the aged phenotypes as well as to physical impairments, syndromes and disability in elderfy people. The insights such research will provide apply to (1) designing diagnostic tests that can quantify precisely physical impairment in elderiy people, (2) designing more effective therapy programs for elderiy people who are already impaired, (3) designing protocols, such as exercise protocols, for prevention of physical impairments in elderiy people. Areas of particular interest include aging, gait on regular and irregular surfaces, mobility, fall-related injuries, as well as female pelvic floor function, urinary incontinence and prolapse, and (4) in transferring technology from bench to bedside. The latter goals are consistent with the CDC Injury Prevention Agenda 2009-2018 (National Center for Injury Prevention and Control, 2009).

无论基本的生理或神经系统机制，有关移动性丧失的问题，电机的恶化控制，对即将跌倒的反应，维持平衡和姿势控制，肌肉的变化最终的收缩特征和维护持续性是生物力学问题（Ashton-Miller＆Alexander，2003年）。从生物力学和其他生理测量。特别是生物力学核心将有助于 UM胡椒中心的使命是通过研究某些机制的研究预测变量和修改变量较早的生活可能会影响老年表型的表达。生物力学研究的应用：资助研究和研究有足够的理由有助于研究生物力学和其他生理机制的作用的训练老年人的衰老表型以及老年人的身体障碍，综合征和残疾。这这些研究的见解将适用于（1）设计可以准确量化的诊断测试老年人的身体障碍，（2）为老年人设计更有效的治疗计划（3）设计协议，例如锻炼方案，以防止身体老年人的障碍。特别感兴趣的区域包括衰老，常规表面和不规则表面的步态，流动性，与跌倒有关的伤害以及女性骨盆底功能，尿失禁和脱垂，以及（4）将技术从长凳转移到床边。后一个目标与预防CDC伤害一致议程2009-2018（国家伤害预防与控制中心，2009年）。